2012

Regulatory RNAs

Basics, Methods and Applications

Editors:

ISBN: 978-3-642-22516-1 (Print) 978-3-642-22517-8 (Online)

Table of contents (21 chapters)

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  1. Front Matter

    Pages i-ix

  2. BASICS

    1. Front Matter

      Pages 1-1

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      Book Chapter

      Pages 3-22

      Renaissance of the Regulatory RNAs

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      Book Chapter

      Pages 23-48

      Diversity, Overlap, and Relationships in the Small RNA Landscape

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      Book Chapter

      Pages 49-71

      Fragments of Small Nucleolar RNAs as a New Source for Noncoding RNAs

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      Book Chapter

      Pages 73-109

      Small Regulatory RNAs (sRNAs): Key Players in Prokaryotic Metabolism, Stress Response, and Virulence

    6. Book Chapter

      Pages 111-149

      The Canonical RNA Interference Pathway in Animals

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      Book Chapter

      Pages 151-174

      Generation of Functional Long Noncoding RNA Through Transcription and Natural Selection

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      Book Chapter

      Pages 175-195

      MicroRNA Regulation of Neuronal Differentiation and Plasticity

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      Book Chapter

      Pages 197-226

      Long Noncoding RNA Function and Expression in Cancer

  3. METHODS

    1. Front Matter

      Pages 227-227

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      Book Chapter

      Pages 229-251

      Expression Profiling of ncRNAs Employing RNP Libraries and Custom LNA/DNA Microarray Analysis

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      Book Chapter

      Pages 253-271

      Targeted Methods to Improve Small RNA Profiles Generated by Deep Sequencing

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      Book Chapter

      Pages 273-293

      Biocomputational Identification of Bacterial Small RNAs and Their Target Binding Sites

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      Book Chapter

      Pages 295-317

      Identifying Functional miRNA Targets Using Overexpression and Knockdown Methods

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      Book Chapter

      Pages 319-340

      Identification of lncRNAs Using Computational and Experimental Approaches

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      Book Chapter

      Pages 341-370

      Experimental Analyses of RNA-Based Regulations in Bacteria

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      Book Chapter

      Pages 371-384

      Microregulators Ruling Over Pluripotent Stem Cells

  4. APPLICATIONS

    1. Front Matter

      Pages 385-385

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      Book Chapter

      Pages 387-408

      The Role of RNA Interference in Targeting the Cancer Stem Cell and Clinical Trials for Cancer

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      Book Chapter

      Pages 409-442

      MicroRNAs in Development, Stem Cell Differentiation, and Regenerative Medicine

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      Book Chapter

      Pages 443-473

      The Role of MicroRNAs in Neurodegenerative Diseases: Implications for Early Detection and Treatment

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      Book Chapter

      Pages 475-503

      siRNA Therapeutic Design: Tools and Challenges

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      Book Chapter

      Pages 505-521

      Artificial MicroRNA and Its Applications

  5. Back Matter

    Pages 547-552

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