Modeling Fragile X Syndrome

Editors:

ISBN: 978-3-642-21648-0 (Print) 978-3-642-21649-7 (Online)

Table of contents (19 chapters)

  1. Front Matter

    Pages i-xi

  2. Ex Vivo Models

    1. Front Matter

      Pages 13-13

    2. No Access

      Book Chapter

      Pages 1-12

      Introduction: Reminiscing on Models and Modeling

    3. No Access

      Book Chapter

      Pages 15-31

      Probing Astrocyte Function in Fragile X Syndrome

    4. No Access

      Book Chapter

      Pages 33-40

      Neural Stem Cells

    5. No Access

      Book Chapter

      Pages 41-59

      Fragile X Mental Retardation Protein (FMRP) and the Spinal Sensory System

    6. No Access

      Book Chapter

      Pages 61-80

      The Role of the Postsynaptic Density in the Pathology of the Fragile X Syndrome

  3. Non-Mouse Eukaryote Models

    1. Front Matter

      Pages 81-81

    2. No Access

      Book Chapter

      Pages 83-117

      Behavior in a Drosophila Model of Fragile X

    3. No Access

      Book Chapter

      Pages 119-156

      Molecular and Genetic Analysis of the Drosophila Model of Fragile X Syndrome

    4. No Access

      Book Chapter

      Pages 157-164

      Fragile X Mental Retardation Protein and Stem Cells

    5. No Access

      Book Chapter

      Pages 165-179

      Manipulating the Fragile X Mental Retardation Proteins in the Frog

    6. No Access

      Book Chapter

      Pages 181-197

      Exploring the Zebra Finch Taeniopygia guttata as a Novel Animal Model for the Speech–Language Deficit of Fragile X Syndrome

  4. Novel Mouse Models

    1. Front Matter

      Pages 199-199

    2. No Access

      Book Chapter

      Pages 201-221

      Neuroendocrine Alterations in the Fragile X Mouse

    3. No Access

      Book Chapter

      Pages 223-241

      Taking STEPs Forward to Understand Fragile X Syndrome

    4. No Access

      Book Chapter

      Pages 243-253

      Fmr-1 as an Offspring Genetic and a Maternal Environmental Factor in Neurodevelopmental Disease

    5. No Access

      Book Chapter

      Pages 255-269

      Mouse Models of the Fragile X Premutation and the Fragile X Associated Tremor/Ataxia Syndrome

  5. The Human Model

    1. Front Matter

      Pages 271-271

    2. No Access

      Book Chapter

      Pages 273-279

      Clinical Aspects of the Fragile X Syndrome

    3. No Access

      Book Chapter

      Pages 281-295

      Fragile X Syndrome: A Psychiatric Perspective

    4. No Access

      Book Chapter

      Pages 297-335

      Fragile X Syndrome and Targeted Treatment Trials

    5. No Access

      Book Chapter

      Pages 337-357

      The Fragile X-Associated Tremor Ataxia Syndrome

  6. Missing Models

    1. Front Matter

      Pages 359-359

    2. No Access

      Book Chapter

      Pages 361-383

      Vignettes: Models in Absentia

  7. Back Matter

    Pages 385-390