Effect-Directed Analysis of Complex Environmental Contamination


ISBN: 978-3-642-18383-6 (Print) 978-3-642-18384-3 (Online)

Table of contents (13 chapters)

  1. Front Matter

    Pages i-xviii

  2. Chapter

    Pages 1-18

    Early Evolution of the Toxicity Identification Evaluation Process: Contributions from the United States Environmental Protection Agency Effluent Testing Program

  3. Chapter

    Pages 19-40

    Recent Developments in Whole Sediment Toxicity Identification Evaluations: Innovations in Manipulations and Endpoints

  4. Chapter

    Pages 41-68

    Considerations for Incorporating Bioavailability in Effect-Directed Analysis and Toxicity Identification Evaluation

  5. Chapter

    Pages 69-82

    Diagnostic Tools for Effect-Directed Analysis of Mutagens, AhR Agonists, and Endocrine Disruptors

  6. Chapter

    Pages 83-118

    Separation Techniques in Effect-Directed Analysis

  7. Chapter

    Pages 119-141

    Simultaneous Screening and Chemical Characterization of Bioactive Compounds Using LC-MS-Based Technologies (Affinity Chromatography)

  8. Chapter

    Pages 143-165

    Advanced GC–MS and LC–MS Tools for Structure Elucidation in Effect-Directed Analysis

  9. Chapter

    Pages 167-198

    Computer Tools for Structure Elucidation in Effect-Directed Analysis

  10. Chapter

    Pages 199-235

    Effect-Directed Analysis of Mutagens in Ambient Airborne Particles

  11. Chapter

    Pages 237-265

    Effect-Directed Analysis of Endocrine Disruptors in Aquatic Ecosystems

  12. Chapter

    Pages 267-283

    Effects-Directed Studies of Pulp and Paper Mill Effluents

  13. Chapter

    Pages 285-313

    Effect-Directed Analysis of Ah-Receptor Mediated Toxicants, Mutagens, and Endocrine Disruptors in Sediments and Biota

  14. Chapter

    Pages 315-339

    Ecological Relevance of Key Toxicants in Aquatic Systems

  15. Back Matter

    Pages 341-345