Two Faces of Evil: Cancer and Neurodegeneration


ISBN: 978-3-642-16601-3 (Print) 978-3-642-16602-0 (Online)

Table of contents (13 chapters)

  1. Front Matter

    Pages i-xiii

  2. Chapter

    Pages 1-16

    Updating the Mammalian Cell Cycle: The Role of Interphase Cdks in Tissue Homeostasis and Cancer

  3. Chapter

    Pages 17-25

    The Role of Cdk5 as a Cell Cycle Suppressor in Post-mitotic Neurons

  4. Chapter

    Pages 27-39

    Actin-SRF Signaling in the Developing and Mature Murine Brain

  5. Chapter

    Pages 41-56

    The E3 Ubiquitin Ligase Ube3A Regulates Synaptic Function Through the Ubiquitination of Arc

  6. Chapter

    Pages 57-71

    Targeting Children’s Brain Tumors: Development of Hedgehog Pathway Inhibitors for Medulloblastoma

  7. Chapter

    Pages 73-82

    Primary Cilia as Switches in Brain Development and Cancer

  8. Chapter

    Pages 83-93

    Nervous System Aging, Degeneration, and the p53 Family

  9. Chapter

    Pages 95-101

    p53, a Molecular Bridge Between Alzheimer’s Disease Pathology and Cancers?

  10. Chapter

    Pages 103-111

    RNA regulation in Neurodegeneration and Cancer

  11. Chapter

    Pages 113-123

    Bridging Environment and DNA: Activity-Induced Epigenetic Modification in the Adult Brain

  12. Chapter

    Pages 125-131

    Intrinsic Brain Signaling Pathways: Targets of Neuron Degeneration

  13. Chapter

    Pages 133-142

    The miRNA System: Bifurcation Points of Cancer and Neurodegeneration

  14. Chapter

    Pages 143-160

    Molecular Mechanisms for the Initiation and Maintenance of Long-Term Memory Storage

  15. Back Matter

    Pages 161-163