2010

Molecular Biology of the SARS-Coronavirus

Editors:

ISBN: 978-3-642-03682-8 (Print) 978-3-642-03683-5 (Online)

Table of contents (19 chapters)

  1. Front Matter

    Pages i-xiii

  2. Viral Entry

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-22

      Cellular Entry of the SARS Coronavirus: Implications for Transmission, Pathogenicity and Antiviral Strategies

    3. No Access

      Book Chapter

      Pages 23-30

      The Cell Biology of the SARS Coronavirus Receptor, Angiotensin-Converting Enzyme 2

    4. No Access

      Book Chapter

      Pages 31-43

      Structural Molecular Insights into SARS Coronavirus Cellular Attachment, Entry and Morphogenesis

  3. Structures Involved in Viral Replication and Gene Expression

    1. Front Matter

      Pages 46-46

    2. No Access

      Book Chapter

      Pages 47-61

      RNA Higher-Order Structures Within the Coronavirus 5′ and 3′ Untranslated Regions and Their Roles in Viral Replication

    3. No Access

      Book Chapter

      Pages 63-72

      Programmed –1 Ribosomal Frameshifting in SARS Coronavirus

  4. Viral Proteins

    1. Front Matter

      Pages 74-74

    2. No Access

      Book Chapter

      Pages 75-98

      Expression and Functions of SARS Coronavirus Replicative Proteins

    3. No Access

      Book Chapter

      Pages 99-114

      SARS Coronavirus Replicative Enzymes: Structures and Mechanisms

    4. No Access

      Book Chapter

      Pages 115-128

      Quaternary Structure of the SARS Coronavirus Main Protease

    5. No Access

      Book Chapter

      Pages 129-151

      The Nucleocapsid Protein of the SARS Coronavirus: Structure, Function and Therapeutic Potential

    6. No Access

      Book Chapter

      Pages 153-166

      SARS Coronavirus Accessory Gene Expression and Function

    7. No Access

      Book Chapter

      Pages 167-175

      SARS Accessory Proteins ORF3a and 9b and Their Functional Analysis

    8. No Access

      Book Chapter

      Pages 177-191

      Molecular and Biochemical Characterization of the SARS-CoV Accessory Proteins ORF8a, ORF8b and ORF8ab

  5. Viral pathogenesis and host immune response

    1. Front Matter

      Pages 194-194

    2. No Access

      Book Chapter

      Pages 195-230

      SARS Coronavirus Pathogenesis and Therapeutic Treatment Design

    3. No Access

      Book Chapter

      Pages 231-245

      Modulation of Host Cell Death by SARS Coronavirus Proteins

    4. No Access

      Book Chapter

      Pages 247-258

      SARS Coronavirus and Lung Fibrosis

    5. No Access

      Book Chapter

      Pages 259-278

      Host Immune Responses to SARS Coronavirus in Humans

    6. No Access

      Book Chapter

      Pages 279-288

      The Use of Retroviral Pseudotypes for the Measurement of Antibody Responses to SARS Coronavirus

    7. No Access

      Book Chapter

      Pages 289-304

      SARS Coronavirus Spike Protein Expression in HL-CZ Human Promonocytic Cells: Monoclonal Antibody and Cellular Transcriptomic Analyses

    8. No Access

      Book Chapter

      Pages 305-322

      Signaling Pathways of SARS-CoV In Vitro and In Vivo

  6. Back Matter

    Pages 323-328