Death Receptors and Cognate Ligands in Cancer

Editors:

ISBN: 978-3-642-03044-4 (Print) 978-3-642-03045-1 (Online)

Table of contents (12 chapters)

  1. Front Matter

    Pages i-xiii

  2. No Access

    Book Chapter

    Pages 1-15

    The Role of TNF in Cancer

  3. No Access

    Book Chapter

    Pages 17-47

    Many Checkpoints on the Road to Cell Death:Regulation of Fas–FasL Interactions and Fas Signaling in Peripheral Immune Responses

  4. No Access

    Book Chapter

    Pages 49-61

    FasL Expression and Reverse Signalling

  5. No Access

    Book Chapter

    Pages 63-85

    Impact of TNF-R1 and CD95 Internalization on Apoptotic and Antiapoptotic Signaling

  6. No Access

    Book Chapter

    Pages 87-114

    Ubiquitination and TNFR1 Signaling

  7. No Access

    Book Chapter

    Pages 115-143

    From Biochemical Principles of Apoptosis Induction by TRAIL to Application in Tumour Therapy

  8. No Access

    Book Chapter

    Pages 145-160

    Therapeutic Targeting of TWEAK/Fn14 in Cancer: Exploiting the Intrinsic Tumor Cell Killing Capacity of the Pathway

  9. No Access

    Book Chapter

    Pages 161-182

    APRIL in B-cell Malignancies and Autoimmunity

  10. No Access

    Book Chapter

    Pages 183-190

    Autophagy in Cancer and Chemotherapy

  11. No Access

    Book Chapter

    Pages 191-218

    Glucocorticoid-Mediated Apoptosis Resistance of Solid Tumors

  12. No Access

    Book Chapter

    Pages 219-239

    Targeting Death-Receptors in Radiation Therapy

  13. No Access

    Book Chapter

    Pages 241-273

    Death Ligands Designed to Kill: Development and Application of Targeted Cancer Therapeutics Based on Proapoptotic TNF Family Ligands

  14. Back Matter

    Pages 275-280