2010

Signal Transduction: Pathways, Mechanisms and Diseases

Editors:

ISBN: 978-3-642-02111-4 (Print) 978-3-642-02112-1 (Online)

Table of contents (23 chapters)

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  1. Front Matter

    Pages i-xi

  2. G Proteins and G Protein–Coupled Receptors

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-24

      Traditional GPCR Pharmacology and Beyond

    3. No Access

      Book Chapter

      Pages 25-41

      Regulation of Intraneuronal Trafficking of G-Protein-Coupled Receptors by Neurotransmitters In Vivo

    4. No Access

      Book Chapter

      Pages 43-61

      Small GTPases and Their Role in Regulating G Protein-Coupled Receptor Signal Transduction

    5. No Access

      Book Chapter

      Pages 63-81

      Regulation of G Protein Receptor Coupling, Mood Disorders and Mechanism of Action of Antidepressants

    6. No Access

      Book Chapter

      Pages 83-98

      Dysregulation of G Protein-Coupled Receptor Signaling in Cancer

  3. Growth Factors

    1. Front Matter

      Pages 100-100

    2. No Access

      Book Chapter

      Pages 101-118

      Insulin Signaling in Normal and Diabetic Conditions

    3. No Access

      Book Chapter

      Pages 119-141

      Epidermal Growth Factor (EGF) Receptor Signaling and Cancer

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      Book Chapter

      Pages 143-158

      Leptin Signaling Pathway

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      Book Chapter

      Pages 159-180

      Signaling in Normal and Pathological Angiogenesis

  4. Signaling Platforms

    1. Front Matter

      Pages 182-182

    2. No Access

      Book Chapter

      Pages 183-197

      Spatial and Temporal Control of Cell Signaling by A-Kinase Anchoring Proteins

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      Book Chapter

      Pages 199-217

      Mitochondria, a Platform for Diverse Signaling Pathways

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      Book Chapter

      Pages 219-236

      Mitogen-Activated Protein Kinases and Their Scaffolding Proteins

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      Book Chapter

      Pages 237-253

      Molecular and Functional Determinants of Ca2+ Signaling Microdomains

  5. Nuclear Receptors / Transcription

    1. Front Matter

      Pages 256-256

    2. No Access

      Book Chapter

      Pages 257-272

      Eukaryotic Gene Transcription

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      Book Chapter

      Pages 273-288

      Estrogen Signaling Mechanisms

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      Book Chapter

      Pages 289-309

      Signal Transduction Pathways Involved in Glucocorticoid Actions

  6. Reactive Signaling Molecules

    1. Front Matter

      Pages 312-312

    2. No Access

      Book Chapter

      Pages 313-336

      Cellular Signaling by Reactive Oxygen Species: Biochemical Basis and Physiological Scope

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      Book Chapter

      Pages 337-349

      Soluble Guanylyl Cyclase: The Nitric Oxide Receptor

  7. Cell Cycle, Cell Death and Cancer

    1. Front Matter

      Pages 352-352

    2. No Access

      Book Chapter

      Pages 353-374

      Distinct Roles of the Pocket Proteins in the Control of Cell Cycle

    3. No Access

      Book Chapter

      Pages 375-395

      Activation of the p53 Tumor Suppressor and its Multiple Roles in Cell Cycle and Apoptosis

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