2009

Recent Advances in Transthyretin Evolution, Structure and Biological Functions

Editors:

ISBN: 978-3-642-00645-6 (Print) 978-3-642-00646-3 (Online)

Table of contents (21 chapters)

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  1. Front Matter

    Pages i-xiii

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    Book Chapter

    Pages 1-21

    Mechanisms of Molecular Recognition: Structural Characteristics of Transthyretin Ligand Interactions

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    Book Chapter

    Pages 23-43

    Transthyretin Synthesis During Development and Evolution: What the Marsupials Revealed

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    Book Chapter

    Pages 45-58

    Evolution of Transthyretin Gene Structure

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    Book Chapter

    Pages 59-75

    Evolutionary Insights from Fish Transthyretin

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    Book Chapter

    Pages 77-94

    The Salmonella sp. TLP: A Periplasmic 5-Hydroxyisourate Hydrolase

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    Book Chapter

    Pages 95-108

    Vertebrate 5-Hydroxyisourate Hydrolase Identification, Function, Structure, and Evolutionary Relationship with Transthyretin

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    Book Chapter

    Pages 109-122

    Transthyretin-Related and Transthyretin-like Proteins

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    Book Chapter

    Pages 123-142

    The Transthyretin—Retinol-Binding Protein Complex

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    Book Chapter

    Pages 143-157

    Transthyretin and Retinol-Binding Protein: Implications in Fish Physiology

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    Book Chapter

    Pages 159-171

    Transthyretin and Endocrine Disruptors

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    Book Chapter

    Pages 173-189

    Genetics: Clinical Implications of Transthyretin Amyloidosis

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    Book Chapter

    Pages 191-200

    Molecular Pathogenesis Associated with Familial Amyloidotic Polyneuropathy

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    Book Chapter

    Pages 201-214

    Histidine 31: The Achilles' Heel of Human Transthyretin. Microheterogeneity is Not Enough to Understand the Molecular Causes of Amyloidogenicity

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    Book Chapter

    Pages 215-238

    New Therapeutic Approaches for Familial Amyloidotic Polyneuropathy (FAP)

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    Book Chapter

    Pages 239-260

    Liver Transplantation for Transthyretin Amyloidosis

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    Book Chapter

    Pages 261-280

    Mouse Models of Transthyretin Amyloidosis

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    Book Chapter

    Pages 281-295

    What Have We Learned from Transthyretin-Null Mice: Novel Functions for Transthyretin?

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    Book Chapter

    Pages 297-310

    Transthyretin Null Mice: Developmental Phenotypes

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    Book Chapter

    Pages 311-328

    Transthyretin Null Mice as a Model to Study the Involvement of Transthyretin in Neurobiology: From Neuropeptide Processing to Nerve Regeneration

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    Book Chapter

    Pages 329-357

    Plasma Transthyretin Reflects the Fluctuations of Lean Body Mass in Health and Disease

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