Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunology


ISBN: 978-3-540-75202-8 (Print) 978-3-540-75203-5 (Online)

Table of contents (10 chapters)

  1. Front Matter

    Pages i-xiii

  2. Immunodeficiency

    1. Chapter

      Pages 3-26

      The Forward Genetic Dissection of Afferent Innate Immunity

    2. Chapter

      Pages 27-57

      Genetic Analysis of Resistance to Infections in Mice: A/J meets C57BL/6J

    3. Chapter

      Pages 59-83

      Host Defenses Against Human Papillomaviruses: Lessons from Epidermodysplasia Verruciformis

    4. Chapter

      Pages 85-100

      Innate Resistance to Flavivirus Infections and the Functions of 2′-5′ Oligoadenylate Synthetases

    5. Chapter

      Pages 101-122

      Cmv1 and Natural Killer Cell Responses to Murine Cytomegalovirus Infection

    6. Chapter

      Pages 123-148

      Genetic Dissection of Host Resistance to Mycobacterium tuberculosis: The sst1 Locus and the Ipr1 Gene

  3. Self-Reactivity

    1. Chapter

      Pages 151-168

      Scurfy, the Foxp3 Locus, and the Molecular Basis of Peripheral Tolerance

    2. Chapter

      Pages 169-184

      Fevers, Genes, and Innate Immunity

    3. Chapter

      Pages 185-200

      Itchy Mice: The Identification of a New Pathway for the Development of Autoimmunity

    4. Chapter

      Pages 201-215

      TIM Gene Family and Their Role in Atopic Diseases

  4. Back Matter

    Pages 217-220