Modern Anesthetics

ISBN: 978-3-540-72813-9 (Print) 978-3-540-74806-9 (Online)

Table of contents (22 chapters)

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  1. Front Matter

    Pages i-xv

  2. Molecular Mechanisms of Anesthetic Action

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      Pages 3-29

      The Site of Anesthetic Action

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      Pages 31-51

      Inhibitory Ligand-Gated Ion Channels as Substrates for General Anesthetic Actions

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      Pages 53-84

      Actions of Anesthetics on Excitatory Transmitter-Gated Channels

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      Pages 85-92

      Voltage-Gated Ion Channels

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      Pages 93-117

      G-Protein-Coupled Receptors

  3. Modern Inhalation Anesthetics

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      Pages 121-142

      Inhalation Anaesthesia: From Diethyl Ether to Xenon

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      Pages 143-157

      General Anesthetics and Long-Term Neurotoxicity

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      Pages 159-186

      Special Aspects of Pharmacokinetics of Inhalation Anesthesia

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      Pages 187-207

      Inhalational Anaesthetics and Cardioprotection

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      Pages 209-223

      Non-Immobilizing Inhalational Anesthetic-Like Compounds

  4. Modern Intravenous Anesthetics

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      Pages 227-252

      Propofol

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      Pages 253-266

      Pharmacokinetics and Pharmacodynamics of GPI 15715 or Fospropofol (Aquavan Injection) — A Water-Soluble Propofol Prodrug

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      Pages 267-282

      Etomidate and Other Non-Barbiturates

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      Pages 283-311

      Remifentanil and Other Opioids

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      Pages 313-333

      Ketamine

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      Pages 335-360

      Midazolam and Other Benzodiazepines

  5. Pharmacokinetics-Pharmacodynamics Based Administration of Anesthetics

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      Book Chapter

      Pages 363-377

      The Effect of Altered Physiological States on Intravenous Anesthetics

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      Book Chapter

      Pages 379-408

      Anesthetics Drug Pharmacodynamics

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      Book Chapter

      Pages 409-423

      Defining Depth of Anesthesia

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      Book Chapter

      Pages 425-450

      Target Controlled Anaesthetic Drug Dosing

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