The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies

ISBN: 978-3-540-74385-9 (Print) 978-3-540-74386-6 (Online)

Table of contents (21 chapters)

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  1. Front Matter

    Pages I-X

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    Book Chapter

    Pages 1-17

    Tumorigenesis

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    Pages 19-37

    Tumor Growth and Cell Proliferation

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    Pages 39-50

    Tumor Angiogenesis

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    Book Chapter

    Pages 51-92

    Pathophysiology of Solid Tumors

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    Pages 93-115

    Adhesion, Invasion, Integrins, and Beyond

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    Book Chapter

    Pages 117-128

    The Biology of Cancer Metastasis

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    Pages 129-145

    Role of the Immune System in Cancer Development and Therapeutic Implications

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    Pages 147-151

    Tumor Detection by Biological Markers

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    Book Chapter

    Pages 153-167

    Tumor Imaging with Special Emphasis on the Role of Positron Emission Tomography in Radiation Treatment Planning

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    Pages 169-190

    Quantitative Cell Kill of Radio- and Chemotherapy

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    Pages 191-219

    The Impact of Molecularly Targeted Therapy in Multi-Modality Therapy

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    Pages 221-241

    Target-Based Interventions to Treat Radiation-Induced Lung Injury

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    Book Chapter

    Pages 243-250

    Mechanisms of Treatment Resistance: Molecular and Clinical Examples for Radio- and Chemotherapy

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    Book Chapter

    Pages 251-271

    DNA Repair and Cell Cycle Regulation After Ionizing Irradiation

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    Book Chapter

    Pages 273-290

    Physiological Mechanisms of Treatment Resistance

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    Book Chapter

    Pages 291-298

    Influence of Time Factor and Repopulation on Treatment Resistance

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    Book Chapter

    Pages 299-311

    Molecular Tools, Expression Profiling

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    Book Chapter

    Pages 313-321

    Strategies of Gene Transfer and Silencing, and Technical Considerations

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    Book Chapter

    Pages 323-334

    Tumor Biology’s Impact on Clinical Cure Rates

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    Book Chapter

    Pages 335-346

    Dose-Escalated High-Precision Radiotherapy: a Method to Overcome Variations in Biology and Radiosensitivity Limiting the Success of Conventional Approaches?

  22. Back Matter

    Pages 355-367

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