Interferon: The 50th Anniversary

Editors:

ISBN: 978-3-540-71328-9 (Print) 978-3-540-71329-6 (Online)

Table of contents (17 chapters)

  1. Front Matter

    Pages i-ix

  2. Refletions

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-7

      How to Chase a Red Herring and Come up with a Smallmouth Bass

    3. No Access

      Book Chapter

      Pages 9-22

      Interferon Research BC (Before Cloning)

    4. No Access

      Book Chapter

      Pages 23-37

      Purification and Cloning of Interferon Alpha

  3. Interferons and Their Signaling Pathways

    1. Front Matter

      Pages 39-39

    2. No Access

      Book Chapter

      Pages 41-70

      Type I Interferon: The Ever Unfolding Story

    3. No Access

      Book Chapter

      Pages 71-95

      The Receptor of the Type I Interferon Family

    4. No Access

      Book Chapter

      Pages 97-117

      IFN-γ: Recent Advances in Understanding Regulation of Expression, Biological Functions, and Clinical Applications

    5. No Access

      Book Chapter

      Pages 119-154

      Cell Type-Specific Signaling in Response to Interferon-γ

    6. No Access

      Book Chapter

      Pages 155-163

      Interferon Research: Impact on Understanding Transcriptional Control

  4. Recognition of Pathogens, Molecular Mechanism of Interferon Beta Induction

    1. Front Matter

      Pages 165-165

    2. No Access

      Book Chapter

      Pages 167-192

      TLR-Mediated Activation of Type I IFN During Antiviral Immune Responses: Fighting the Battle to Win the War

    3. Book Chapter

      Pages 193-205

      Regulation of Antiviral Innate Immune Responses by RIG-I Family of RNA Helicases

    4. No Access

      Book Chapter

      Pages 207-230

      Beyond Double-Stranded RNA-Type I IFN Induction by 3pRNA and Other Viral Nucleic Acids

  5. Interferon-Induced Genes

    1. Front Matter

      Pages 231-231

    2. No Access

      Book Chapter

      Pages 233-250

      The Interferon-Stimulated Genes: Targets of Direct Signaling by Interferons, Double-Stranded RNA, and Viruses

    3. No Access

      Book Chapter

      Pages 253-292

      Structure and Function of the Protein Kinase R

  6. Virus Defense

    1. Front Matter

      Pages 293-293

    2. Book Chapter

      Pages 295-313

      Viral Regulation and Evasion of the Host Response

    3. Book Chapter

      Pages 315-334

      Pathogenic Viruses: Smart Manipulators of the Interferon System

  7. Role of Interferon in Viral Infection and Autoimmunity

    1. Front Matter

      Pages 335-335

    2. No Access

      Book Chapter

      Pages 337-357

      Type I Interferon During Viral Infections: Multiple Triggers for a Multifunctional Mediator

    3. No Access

      Book Chapter

      Pages 359-386

      Type I Interferon in Systemic Lupus Erythematosus

  8. Back Matter

    Pages 387-391