cGMP: Generators, Effectors and Therapeutic Implications

ISBN: 978-3-540-68960-7 (Print) 978-3-540-68964-5 (Online)

Table of contents (24 chapters)

previous Page of 2
  1. Front Matter

    Pages i-xiv

  2. Basic Generators and Effectors

    1. No Access

      Book Chapter

      Pages 1-14

      A Short History of cGMP, Guanylyl Cyclases, and cGMP-Dependent Protein Kinases

    2. No Access

      Book Chapter

      Pages 17-31

      Biochemistry of Soluble Guanylate Cyclase

    3. No Access

      Book Chapter

      Pages 33-46

      Genetic Mouse Models of the NO Receptor ‘Soluble’ Guanylyl Cyclases

    4. No Access

      Book Chapter

      Pages 47-69

      Function and Dysfunction of Mammalian Membrane Guanylyl Cyclase Receptors: Lessons from Genetic Mouse Models and Implications for Human Diseases

    5. No Access

      Book Chapter

      Pages 71-92

      Phosphodiesterases in the Central Nervous System

    6. No Access

      Book Chapter

      Pages 93-109

      Structural and Biochemical Aspects of Tandem GAF Domains

    7. No Access

      Book Chapter

      Pages 111-136

      Cyclic Nucleotide-Gated Channels

    8. No Access

      Book Chapter

      Pages 137-162

      cGMP Regulated Protein Kinases (cGK)

    9. No Access

      Book Chapter

      Pages 163-193

      cGK Substrates

    10. No Access

      Book Chapter

      Pages 195-228

      Biochemical Detection of cGMP From Past to Present: An Overview

    11. No Access

      Book Chapter

      Pages 229-243

      Novel Techniques for Real-Time Monitoring of cGMP in Living Cells

  3. Pharmacology of cGMP

    1. No Access

      Book Chapter

      Pages 247-276

      NO and sGC-Stimulating NO Donors

    2. No Access

      Book Chapter

      Pages 277-308

      NO-Independent, Haem-Dependent Soluble Guanylate Cyclase Stimulators

    3. No Access

      Book Chapter

      Pages 309-339

      NO- and Haem-Independent Soluble Guanylate Cyclase Activators

    4. No Access

      Book Chapter

      Pages 341-366

      Natriuretic Peptides: Their Structures, Receptors, Physiologic Functions and Therapeutic Applications

    5. No Access

      Book Chapter

      Pages 367-408

      Cyclic GMP-Hydrolyzing Phosphodiesterases

    6. No Access

      Book Chapter

      Pages 409-421

      cGMP-Dependent Protein Kinase Modulators

    7. No Access

      Book Chapter

      Pages 423-443

      cGMP-Dependent Protein Kinase as a Modifier of Behaviour

  4. Clinical Applications

    1. No Access

      Book Chapter

      Pages 447-467

      cGMP in the Vasculature

    2. No Access

      Book Chapter

      Pages 469-483

      Modulating cGMP to Treat Lung Diseases

previous Page of 2