2014

Molecular Mechanisms of Angiogenesis

From Ontogenesis to Oncogenesis

Editors:

ISBN: 978-2-8178-0465-1 (Print) 978-2-8178-0466-8 (Online)

Table of contents (24 chapters)

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  1. Front Matter

    Pages i-xi

  2. Angiogenesis During Embryonic Development

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-23

      Emergence of Endothelial Cells During Vascular Development

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      Book Chapter

      Pages 25-44

      Lymphatic Vascular Morphogenesis

  3. The Physiological Angiogenic Signal: Cellular and Molecular Mechanisms

    1. Front Matter

      Pages 45-45

    2. No Access

      Book Chapter

      Pages 47-75

      Finding New Partnerships: The Function of Individual Extracellular Receptor Domains in Angiogenic Signalling by VEGF Receptors

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      Book Chapter

      Pages 77-97

      Wnt/Frizzled Signaling in the Vasculature

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      Book Chapter

      Pages 99-119

      BMP9, BMP10, and ALK1: An Emerging Vascular Signaling Pathway with Therapeutic Applications

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      Book Chapter

      Pages 121-148

      Apelin Signaling in Retinal Angiogenesis

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      Book Chapter

      Pages 149-167

      Emerging Role of the Two Related Basic Helix-Loop-Helix Proteins TAL1 and LYL1 in Angiogenesis

  4. Hypoxia, Ischemia and Angiogenesis

    1. Front Matter

      Pages 169-169

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      Book Chapter

      Pages 171-197

      Hypoxia and Extracellular Matrix Remodeling

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      Book Chapter

      Pages 199-217

      Sphingosine-1-Phosphate in Hypoxic Signaling

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      Book Chapter

      Pages 219-233

      Reciprocal Crosstalk Between Angiogenesis and Metabolism

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      Book Chapter

      Pages 235-264

      Endothelial Progenitor Cells and Cardiovascular Ischemic Diseases: Characterization, Functions, and Potential Clinical Applications

  5. Tumor Angiogenesis

    1. Front Matter

      Pages 265-265

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      Book Chapter

      Pages 267-282

      Endothelial Cell Reactions to Oxygen: Implications for Cancer

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      Book Chapter

      Pages 283-306

      Tumor Angiogenesis and Lymphangiogenesis: Microenvironmental Soil for Tumor Progression and Metastatic Dissemination

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      Book Chapter

      Pages 307-324

      Angiogenesis and Invasion in Malignant Glioma: Friends or Foes?

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      Book Chapter

      Pages 325-337

      Role of Endothelial Cells in Tumor Escape from Immunity

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      Book Chapter

      Pages 339-352

      Tumor High Endothelial Venules and Lymphocyte Trafficking

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      Book Chapter

      Pages 353-372

      Posttranscriptional Regulation of Angiogenesis Through AU-Rich mRNA Degradation: Potential Application in Cancer Therapy

  6. Anti-angiogenic Drugs in Human Cancer Therapy

    1. Front Matter

      Pages 373-373

    2. No Access

      Book Chapter

      Pages 375-382

      Antiangiogenic Drugs in Cancer Therapy: Effect on Advanced Renal Cell Carcinoma

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      Book Chapter

      Pages 383-396

      Anti-angiogenic Therapies in Colorectal Cancer

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      Book Chapter

      Pages 397-419

      Resistance to Antiangiogenic Treatments via Upregulation of Substitution Pathways

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