2008

Electrical Diseases of the Heart

Genetics, Mechanisms, Treatment, Prevention

ISBN: 978-1-84628-853-1 (Print) 978-1-84628-854-8 (Online)

Table of contents (69 chapters)

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  1. Front Matter

    Pages i-xxvi

  2. Basic Foundations of Normal and Abnormal Cardiac Electrical Activity

    1. Front Matter

      Pages 1-1

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      Book Chapter

      Pages 3-10

      The Past and Promise of Basic Cardiac Electrophysiology

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      Pages 11-23

      Basic Physiology of Ion Channel Function

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      Pages 24-36

      Developmental Aspects of the Electrophysiology of the Heart: Function Follows Form

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      Pages 37-51

      Anatomic and Histopathological Characteristics of the Conductive Tissues of the Heart

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      Pages 52-64

      Neural Regulation of the Heart in Health and Disease

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      Pages 65-132

      Mechanisms of Cardiac Arrhythmia

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      Pages 133-144

      Mechanisms of Action of Antiarrhythmic Drugs

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      Pages 145-160

      Mechanoelectrical Interactions and Their Role in Electrical Function of the Heart

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      Pages 161-169

      The Role of Cellular Sodium and Calcium Loading in Cardiac Energetics and Arrhythmogenesis: Contribution of the Late Sodium Current

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      Pages 170-186

      Sodium Ion Channelopathies

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      Pages 187-193

      L-type Calcium Channel Disease

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      Pages 194-206

      K+ Channelopathies (I Ks and I Kr)

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      Pages 207-217

      Channelopathies of Cardiac Inwardly Rectifying Potassium Channels

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      Pages 218-231

      Calcium Release Channels (Ryanodine Receptors) and Arrhythmogenesis

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      Pages 232-246

      Caveolae and Arrhythmogenesis

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      Pages 247-260

      Senescence and Arrhythmogenesis

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      Pages 261-280

      Comparisons of Substrates Responsible for Atrial Versus Ventricular Fibrillation

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      Pages 281-289

      Single Nucleotide Polymorphisms in Health and Cardiac Disease

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      Pages 290-304

      Electrophysiological remodeling in Dilated Cardiomyopathy and Heart Failure

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      Book Chapter

      Pages 305-315

      Ventricular Electrical Remodeling in Compensated Cardiac Hypertrophy

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