Clinical Trials in Rheumatoid Arthritis and Osteoarthritis

ISBN: 978-1-85233-874-9 (Print) 978-1-84628-742-8 (Online)

Table of contents (18 chapters)

  1. Front Matter

    Pages I-VIII

  2. No Access

    Book Chapter

    Pages 1-3

    Introduction

  3. No Access

    Book Chapter

    Pages 5-36

    Historical and Current Perspectives on Management of Osteoarthritis and Rheumatoid Arthritis

  4. No Access

    Book Chapter

    Pages 37-49

    Development of Biological Therapies for Inflammatory Arthritis

  5. No Access

    Book Chapter

    Pages 51-67

    Study Design and End Points for Rheumatoid Arthritis Trials

  6. No Access

    Book Chapter

    Pages 69-79

    Study Design and End Points in Ankylosing Spondylitis Clinical Trials

  7. No Access

    Book Chapter

    Pages 81-90

    Trial Design and Outcomes in Osteoarthritis

  8. No Access

    Book Chapter

    Pages 91-111

    Ethical Considerations

  9. No Access

    Book Chapter

    Pages 113-122

    Organization of the Clinical Trial by the Sponsor

  10. No Access

    Book Chapter

    Pages 123-134

    Organization of the Trial attheInvestigator Site

  11. No Access

    Book Chapter

    Pages 135-150

    Role of the Imaging Core Laboratory in Rheumatoid Arthritis and Osteoarthritis Clinical Trials

  12. No Access

    Book Chapter

    Pages 151-169

    Biochemical Markers of Rheumatoid Arthritis and Osteoarthritis: Clinical Utility and Practical Considerations

  13. No Access

    Book Chapter

    Pages 171-199

    Data Analysis and Presentation: Writing a Paper for Publication

  14. No Access

    Book Chapter

    Pages 201-221

    Radiographic Imaging End Points in Rheumatoid Arthritis Trials

  15. No Access

    Book Chapter

    Pages 223-234

    Radiography in Clinical Trials Investigating Osteoarthritis

  16. No Access

    Book Chapter

    Pages 235-248

    Use of Quantitative Magnetic Resonance Imaging in the Cross-Sectional and Longitudinal Evaluation of Structural Changes in Knee Osteoarthritis Patients

  17. No Access

    Book Chapter

    Pages 249-274

    Biochemical Markers as Surrogate End Points of Joint Disease

  18. No Access

    Book Chapter

    Pages 275-287

    Role of Genetics and Genomics in Clinical Trials in Osteoarthritis and Rheumatoid Arthritis

  19. No Access

    Book Chapter

    Pages 289-307

    Cost-Effectiveness of New Biologics for Rheumatoid Arthritis and Osteoarthritis

  20. Back Matter

    Pages 309-325