2007

Abeta Peptide and Alzheimer’s Disease

Celebrating a Century of Research

ISBN: 978-1-85233-961-6 (Print) 978-1-84628-440-3 (Online)

Table of contents (16 chapters)

  1. Front Matter

    Pages i-xi

  2. No Access

    Book Chapter

    Pages 1-4

    A Brief Introduction to the History of the β-Amyloid Protein (Aβ) of Alzheimer’s Disease

  3. No Access

    Book Chapter

    Pages 5-36

    The Aβcentric Pathway of Alzheimer’s Disease

  4. No Access

    Book Chapter

    Pages 37-51

    The Function of the Amyloid Precursor Protein Family

  5. No Access

    Book Chapter

    Pages 52-82

    The Involvement of Aβ in the Neuroinflammatory Response

  6. No Access

    Book Chapter

    Pages 83-92

    Amyloid β-Peptide(1-42), Oxidative Stress, and Alzheimer’s Disease

  7. No Access

    Book Chapter

    Pages 93-101

    Amyloid Toxicity, Synaptic Dysfunction, and the Biochemistry of Neurodegeneration in Alzheimer’s Disease

  8. No Access

    Book Chapter

    Pages 102-124

    Aβ Variants and Their Impact on Amyloid Formation and Alzheimer’s Disease Progression

  9. No Access

    Book Chapter

    Pages 125-141

    Copper Coordination by β-Amyloid and the Neuropathology of Alzheimer’s Disease

  10. No Access

    Book Chapter

    Pages 142-158

    Cholesterol and Alzheimer’s Disease

  11. No Access

    Book Chapter

    Pages 159-178

    Amyloid β-Peptide and Central Cholinergic Neurons: Involvement in Normal Brain Function and Alzheimer’s Disease Pathology

  12. No Access

    Book Chapter

    Pages 179-197

    Physiologic and Neurotoxic Properties of Aβ Peptides

  13. No Access

    Book Chapter

    Pages 198-215

    Impact of β-Amyloid on the Tau Pathology in Tau Transgenic Mouse and Tissue Culture Models

  14. No Access

    Book Chapter

    Pages 216-233

    Glial Cells and Aβ Peptides in Alzheimer’s Disease Pathogenesis

  15. No Access

    Book Chapter

    Pages 234-244

    The Role of Presenilins in Aβ-Induced Cell Death in Alzheimer’s Disease

  16. No Access

    Book Chapter

    Pages 245-258

    Immunotherapeutic Approaches to Alzheimer’s Disease

  17. No Access

    Book Chapter

    Pages 259-273

    Mouse Models of Alzheimer’s Disease

  18. Back Matter

    Pages 274-298