2012

The Centrosome

Cell and Molecular Mechanisms of Functions and Dysfunctions in Disease

Editors:

ISBN: 978-1-62703-034-2 (Print) 978-1-62703-035-9 (Online)

Table of contents (22 chapters)

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  1. Front Matter

    Pages i-xiv

  2. Centrosomes in Reproduction

    1. Front Matter

      Pages 1-1

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      Book Chapter

      Pages 3-31

      Centriole Duplication and Inheritance in Drosophila melanogaster

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      Book Chapter

      Pages 33-48

      Sperm Centrioles and Their Dual Role in Flagellogenesis and Cell Cycle of the Zygote

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      Book Chapter

      Pages 49-58

      Centrosomal Functions and Dysfunctions in Cat Spermatozoa

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      Book Chapter

      Pages 59-72

      Nuclear–Centrosome Relationships During Fertilization, Cell Division, Embryo Development, and in Somatic Cell Nuclear Transfer Embryos

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      Book Chapter

      Pages 73-97

      Human Centrosomal Dynamics During Gametogenesis, Fertilization, and Embryogenesis and Its Impact on Fertility: Ultrastructural Analysis

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      Book Chapter

      Pages 99-110

      Asymmetric Centrosome Behavior in Stem Cell Divisions

  3. Cell and Molecular Biology of Centrosomes

    1. Front Matter

      Pages 111-111

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      Book Chapter

      Pages 113-131

      Functional Associations Between the Golgi Apparatus and the Centrosome in Mammalian Cells

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      Book Chapter

      Pages 133-155

      Many Pathways to Destruction: The Role of the Centrosome in, and Its Control by Regulated Proteolysis

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      Book Chapter

      Pages 157-172

      Regulation of the Centrosome Cycle by Protein Degradation

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      Book Chapter

      Pages 173-186

      Molecular Links Between Centrosome Duplication and Other Cell Cycle-Associated Events

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      Book Chapter

      Pages 187-197

      Regulation of Centrosomes by Cyclin-Dependent Kinases

  4. Centrosome Abnormalities in Cancer

    1. Front Matter

      Pages 199-199

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      Book Chapter

      Pages 201-221

      Disruption of Centrosome Duplication Control and Induction of Mitotic Instability by the High-Risk Human Papillomavirus Oncoproteins E6 and E7

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      Book Chapter

      Pages 223-241

      Centrosomes, DNA Damage and Aneuploidy

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      Book Chapter

      Pages 243-253

      Centrosome Regulation and Breast Cancer

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      Book Chapter

      Pages 255-276

      The Role of Centrosomes in Multiple Myeloma

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      Book Chapter

      Pages 277-284

      Centrosomal Amplification and Related Abnormalities Induced by Nucleoside Analogs

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      Book Chapter

      Pages 285-305

      Mechanisms and Consequences of Centrosome Clustering in Cancer Cells

  5. Centrosomes in Other Systems

    1. Front Matter

      Pages 307-307

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      Book Chapter

      Pages 309-326

      Re-evaluation of the Neuronal Centrosome as a Generator of Microtubules for Axons and Dendrites

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      Book Chapter

      Pages 327-346

      Centrosomes and Cell Division in Apicomplexa

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      Book Chapter

      Pages 347-363

      The Centrosome Life Story in Xenopus laevis

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