Clinical Applications of Capillary Electrophoresis

Methods and Protocols

Editors:

ISBN: 978-1-62703-028-1 (Print) 978-1-62703-029-8 (Online)

Table of contents (26 protocols)

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  1. Front Matter

    Pages i-xiii

  2. Overview

    1. Front Matter

      Pages 1-1

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      Pages 3-10

      An Overview of CE in Clinical Analysis

  3. Applications in Clinical Chemistry

    1. Front Matter

      Pages 11-11

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      Pages 13-23

      Monitoring of Arrays of Amino Acids in Clinical Samples Using Capillary Electrophoresis with Contactless Conductivity Detection

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      Pages 25-34

      The Selective Determination of Sulfates, Sulfonates, and Phosphates in Urine by Capillary Electrophoresis/Mass Spectrometry

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      Pages 35-42

      Analysis of Neurotransmitter Amino Acids by CE-LIF Detection in Biological Fluids

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      Pages 43-56

      Expanded Newborn Screening of Inborn Errors of Metabolism by Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry (CE-ESI-MS)

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      Pages 57-66

      Development of an On-Site Measurement System for Salivary Stress-Related Substances Based on Microchip CE

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      Pages 67-78

      Simultaneous Determination of Atenolol and Amiloride by Capillary Electrophoresis with Capacitively Coupled Contactless Conductivity Detection (C4D)

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      Pages 79-85

      A Homogeneous Immunoassay of Thyroxine Based on Microchip Electrophoresis and Chemiluminescence Detection

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      Pages 87-96

      High-Throughput Profiling of the Serum N-Glycome on Capillary Electrophoresis Microfluidics Systems

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      Pages 97-109

      Screening of Matrix Metalloproteinase Inhibitors by Microanalysis with Fluorescence Detection

  4. Applications in Hematology

    1. Front Matter

      Pages 111-111

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      Pages 113-120

      ABO Genotyping by Capillary Electrophoresis

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      Pages 121-130

      Separation of Hemoglobin Variants by Capillary Electrophoresis

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      Pages 131-145

      Newborn Screening for Hemoglobinopathies Using Capillary Electrophoresis

  5. Applications in Bacteriology and Virology

    1. Front Matter

      Pages 147-147

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      Pages 149-154

      Application of CZE in the Differentiation of Staphylococcus aureus Strains

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      Pages 155-163

      Multiplex and Quantitative Pathogen Detection with High-Resolution Capillary Electrophoresis-Based Single-Strand Conformation Polymorphism

    4. Book Protocol

      Pages 165-177

      Application of CGE to Virus Identification

  6. Applications in Disease Biomarker Discovery

    1. Front Matter

      Pages 179-179

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      Pages 181-187

      Capillary Electrophoresis-Based Proteomic Techniques for Biomarker Discovery

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      Pages 189-201

      Integrated Affinity and Electrophoresis Systems for Multiplexed Biomarker Analysis

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      Pages 203-213

      Urinary Proteomics Based on Capillary Electrophoresis Coupled to Mass Spectrometry in Kidney Disease

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      Pages 215-230

      Immunoaffinity, Capillary Electrophoresis, and Statistics for Studying Intact Alpha 1-Acid Glycoprotein Isoforms as an Atherothrombosis Biomarker

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