Bioinformatics and Drug Discovery

Editors:

ISBN: 978-1-61779-964-8 (Print) 978-1-61779-965-5 (Online)

Table of contents (15 protocols)

  1. Front Matter

    Pages i-xii

  2. No Access

    Book Protocol

    Pages 1-13

    Cell Perturbation Screens for Target Identification by RNAi

  3. No Access

    Book Protocol

    Pages 15-31

    Using Functional Genomics to Identify Drug Targets: A Dupuytren’s Disease Example

  4. No Access

    Book Protocol

    Pages 33-53

    Functional Characterization of Human Genes from Exon Expression and RNA Interference Results

  5. No Access

    Book Protocol

    Pages 55-69

    Barcode Sequencing for Understanding Drug–Gene Interactions

  6. No Access

    Book Protocol

    Pages 71-86

    High-Throughput Sequencing of the Methylome Using Two-Base Encoding

  7. No Access

    Book Protocol

    Pages 87-124

    Applications and Limitations of In Silico Models in Drug Discovery

  8. No Access

    Book Protocol

    Pages 125-143

    Compound Collection Preparation for Virtual Screening

  9. No Access

    Book Protocol

    Pages 145-164

    Mapping Between Databases of Compounds and Protein Targets

  10. No Access

    Book Protocol

    Pages 165-194

    Predictive Cheminformatics in Drug Discovery: Statistical Modeling for Analysis of Micro-array and Gene Expression Data

  11. No Access

    Book Protocol

    Pages 195-266

    Advances in Nuclear Magnetic Resonance for Drug Discovery

  12. No Access

    Book Protocol

    Pages 267-278

    Human ABC Transporter ABCG2 in Cancer Chemotherapy: Drug Molecular Design to Circumvent Multidrug Resistance

  13. No Access

    Book Protocol

    Pages 279-296

    Protein Interactions: Mapping Interactome Networks to Support Drug Target Discovery and Selection

  14. No Access

    Book Protocol

    Pages 297-308

    Linking Variants from Genome-Wide Association Analysis to Function via Transcriptional Network Analysis

  15. No Access

    Book Protocol

    Pages 309-335

    Models of Excitation–Contraction Coupling in Cardiac Ventricular Myocytes

  16. No Access

    Book Protocol

    Pages 337-370

    Integration of Multiple Ubiquitin Signals in Proteasome Regulation

  17. Back Matter

    Pages 371-374