Book Volume 10 2012

Ghrelin in Health and Disease


ISBN: 978-1-61779-902-0 (Print) 978-1-61779-903-7 (Online)

Table of contents (16 chapters)

  1. Front Matter

    Pages i-xiv

  2. Chapter

    Pages 1-35

    Ghrelin: A History of Its Discovery

  3. Chapter

    Pages 37-49

    Enzymatic Processing of Ghrelin Precursor

  4. Chapter

    Pages 51-71

    Ghrelin’s Novel Signaling in Islet β-Cells to Inhibit Insulin Secretion and Its Blockade As a Promising Strategy to Treat Type 2 Diabetes

  5. Chapter

    Pages 73-89

    Gastric Ghrelin in the Regulation of Appetite and Metabolism

  6. Chapter

    Pages 91-110

    Ghrelin Regulation of AMPK in the Hypothalamus and Peripheral Tissues

  7. Chapter

    Pages 111-130

    Ghrelin: Neuropeptide Regulator of Metabolism

  8. Chapter

    Pages 131-147

    GOAT and the Regulation of Energy and Glucose Homeostasis

  9. Chapter

    Pages 149-170

    Ghrelin Regulation of Sleep, Circadian Clock, and Body Temperature

  10. Chapter

    Pages 171-180

    Ghrelin Regulation of Learning, Memory, and Neurodegeneration

  11. Chapter

    Pages 181-197

    Ghrelin Antagonism: A Potential Therapeutic Target for Addictive Behaviour Disorders

  12. Chapter

    Pages 199-211

    Ghrelin Receptor Agonists in Cachexia of Human Aging

  13. Chapter

    Pages 213-230

    Use of Ghrelin and Ghrelin Receptor Agonists in Cancer- and Chemotherapy-Induced Cachexia

  14. Chapter

    Pages 231-256

    Ghrelin in Cachexia Associated with End-Stage Renal Disease

  15. Chapter

    Pages 257-266

    Ghrelin Suppression of Autoimmune Encephalomyelitis

  16. Chapter

    Pages 267-275

    Physiological Roles of Des-Acyl Ghrelin

  17. Chapter

    Pages 277-283

    The Ghrelin Receptor (GHSR1a), But Not Ghrelin, Is Essential for Dopamine Receptor-2 (DRD2) Agonist-Induced Anorexia

  18. Back Matter

    Pages 285-290