Cancer Epigenetics

Methods and Protocols

Editors:

ISBN: 978-1-61779-611-1 (Print) 978-1-61779-612-8 (Online)

Table of contents (29 protocols)

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  1. Front Matter

    Pages i-xiii

  2. Early Epigenetic Events in Cancer

    1. Front Matter

      Pages 1-1

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      Pages 3-14

      Epigenetic Markers of Early Tumor Development

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      Pages 15-31

      Epigenetics of Solid Cancer Stem Cells

  3. Cancer Specific Type Epigenetic Changes

    1. Front Matter

      Pages 33-33

    2. No Access

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      Pages 35-45

      DNA Methylation and Histone Modifications in Breast Cancer

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      Pages 47-66

      DNA Methylation Changes in Prostate Cancer

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      Pages 67-109

      DNA Methylation in Promoter Region as Biomarkers in Prostate Cancer

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      Pages 111-118

      Epigenetics of Bladder Cancer

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      Pages 119-137

      Epigenetics in Myeloid Malignancies

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      Pages 139-153

      The Epigenetics of Brain Tumors

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      Pages 155-176

      DNA Methylation Changes in Cervical Cancers

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      Pages 177-185

      Epigenetics of Colon Cancer

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      Pages 187-206

      Promoter Methylation in Head and Neck Tumorigenesis

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      Pages 207-219

      Epigenome and DNA Methylation in Oral Squamous Cell Carcinoma

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      Pages 221-239

      Clinical Implications of Epigenetic Alterations in Human Thoracic Malignancies: Epigenetic Alterations in Lung Cancer

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      Pages 241-251

      The Role of MicroRNAs in the Management of Liver Cancer

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      Pages 253-269

      Epigenetics in Ovarian Cancer

  4. Methods and Technologies used for Epigenetic Changes’ Detection

    1. Front Matter

      Pages 271-271

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      Pages 273-280

      DNA Methylation in Pancreatic Cancer: Protocols for the Isolation of DNA and Bisulfite Modification

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      Pages 281-292

      Detection and Analysis of DNA Methylation by Pyrosequencing

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      Pages 293-302

      Screening for miRNA Expression Changes Using Quantitative PCR (Q-PCR)

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      Pages 303-317

      Genome-Wide Methylation Analysis

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      Pages 319-328

      Microarray for Epigenetic Changes: Gene Expression Arrays

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