Targeted Therapeutics in Melanoma

Editors:

ISBN: 978-1-61779-406-3 (Print) 978-1-61779-407-0 (Online)

Table of contents (18 chapters)

  1. Front Matter

    Pages i-xiv

  2. Advances in Melanoma Biology

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-15

      Molecular Targets and Subtypes in Melanoma

    3. No Access

      Book Chapter

      Pages 17-25

      Melanoma Genomics

    4. No Access

      Book Chapter

      Pages 27-40

      Predictive Biomarkers as a Guide to Future Therapy Selection in Melanoma

  3. Signaling Molecules as Molecular Targets

    1. Front Matter

      Pages 41-41

    2. No Access

      Book Chapter

      Pages 43-61

      KIT as a Therapeutic Target for Melanoma

    3. No Access

      Book Chapter

      Pages 63-76

      Targeted Inhibition of B-Raf

    4. No Access

      Book Chapter

      Pages 77-87

      The Notch and β-Catenin Pathways

    5. No Access

      Book Chapter

      Pages 89-105

      STAT3 and Src Signaling in Melanoma

    6. No Access

      Book Chapter

      Pages 107-123

      Targeting the mTOR, PI3K, and AKT Pathways in Melanoma

    7. No Access

      Book Chapter

      Pages 125-153

      Targeting Apoptotic Pathways in Melanoma

    8. No Access

      Book Chapter

      Pages 155-184

      Anti-Angiogenesis Therapy in Melanoma

  4. Rational Immunotherapy Approaches in Melanoma

    1. Front Matter

      Pages 185-185

    2. No Access

      Book Chapter

      Pages 187-205

      Melanoma Antigens Recognized by T Lymphocytes

    3. No Access

      Book Chapter

      Pages 207-232

      Melanoma Vaccines

    4. No Access

      Book Chapter

      Pages 233-272

      Adoptive Cell Therapy for the Treatment of Metastatic Melanoma

    5. No Access

      Book Chapter

      Pages 273-289

      Anti-CTLA-4 Monoclonal Antibodies

    6. No Access

      Book Chapter

      Pages 291-306

      Anti-PD-1 and Anti-B7-H1/PD-L1 Monoclonal Antibodies

    7. No Access

      Book Chapter

      Pages 307-331

      Treatment of Melanoma with Agonist Immune Costimulatory Agents

    8. No Access

      Book Chapter

      Pages 333-351

      Novel Cytokines for Immunotherapy of Melanoma

    9. No Access

      Book Chapter

      Pages 353-369

      Modulating the Tumor Microenvironment

  5. Back Matter

    Pages 371-377