Adeno-Associated Virus

Methods and Protocols

Editors:

ISBN: 978-1-61779-369-1 (Print) 978-1-61779-370-7 (Online)

Table of contents (18 protocols)

  1. Front Matter

    Pages i-xiii

  2. No Access

    Book Protocol

    Pages 1-23

    Adeno-Associated Virus Biology

  3. No Access

    Book Protocol

    Pages 25-46

    Design and Construction of Functional AAV Vectors

  4. No Access

    Book Protocol

    Pages 47-92

    AAV Capsid Structure and Cell Interactions

  5. No Access

    Book Protocol

    Pages 93-118

    Exploiting Natural Diversity of AAV for the Design of Vectors with Novel Properties

  6. No Access

    Book Protocol

    Pages 119-140

    Gene Therapy in Skeletal Muscle Mediated by Adeno-Associated Virus Vectors

  7. No Access

    Book Protocol

    Pages 141-157

    AAV-Mediated Liver-Directed Gene Therapy

  8. No Access

    Book Protocol

    Pages 159-177

    Recombinant AAV Delivery to the Central Nervous System

  9. No Access

    Book Protocol

    Pages 179-218

    Adeno-Associated Virus Mediated Gene Therapy for Retinal Degenerative Diseases

  10. No Access

    Book Protocol

    Pages 219-237

    Adeno-Associated Virus Vector Delivery to the Heart

  11. No Access

    Book Protocol

    Pages 239-258

    Evaluation of the Fate of rAAV Genomes Following In Vivo Administration

  12. No Access

    Book Protocol

    Pages 259-272

    Measuring Immune Responses to Recombinant AAV Gene Transfer

  13. No Access

    Book Protocol

    Pages 273-300

    Modification and Labeling of AAV Vector Particles

  14. No Access

    Book Protocol

    Pages 301-315

    AAV-Mediated Gene Targeting

  15. No Access

    Book Protocol

    Pages 317-337

    Preclinical Study Design for rAAV

  16. No Access

    Book Protocol

    Pages 339-359

    Biodistribution and Shedding of AAV Vectors

  17. No Access

    Book Protocol

    Pages 361-404

    Production and Purification of Recombinant Adeno-Associated Vectors

  18. No Access

    Book Protocol

    Pages 405-428

    rAAV Vector Product Characterization and Stability Studies

  19. No Access

    Book Protocol

    Pages 429-457

    rAAV Human Trial Experience

  20. Back Matter

    Pages 459-462