Nuclear Reprogramming and Stem Cells


ISBN: 978-1-61779-224-3 (Print) 978-1-61779-225-0 (Online)

Table of contents (20 chapters)

  1. Front Matter

    Pages i-xv

  2. Chapter

    Pages 1-2


  3. Chapter

    Pages 3-6

    Introduction: Stem Cells – What Next?

  4. Chapter

    Pages 7-24

    Inherent Nuclear Reprogramming in Mammalian Embryos

  5. Chapter

    Pages 25-44

    Epigenetic Reprogramming During Somatic Cell Nuclear Transfer and the Development of Primordial Germ Cells

  6. Chapter

    Pages 45-57

    Epigenetic Reprogramming with Oocyte Molecules

  7. Chapter

    Pages 59-69

    Cell Fusion-Mediated Nuclear Reprogramming of Somatic Cells

  8. Chapter

    Pages 71-82

    Generation of Induced Pluripotent Stem Cells from Somatic Cells

  9. Chapter

    Pages 83-97

    The Consequences of Reprogramming a Somatic Cell for Mitochondrial DNA Transmission, Inheritance and Replication

  10. Chapter

    Pages 99-112

    The Function of Nanog in Pluripotency

  11. Chapter

    Pages 113-125

    Function of Oct3/4 and Sox2 in Pluripotency

  12. Chapter

    Pages 127-140

    Generation of Neural Cells from Pluripotent Stem Cells

  13. Chapter

    Pages 141-153

    Noncell Autonomous Reprogramming to a Pluripotent State

  14. Chapter

    Pages 155-175

    Toward Regeneration of Retinal Function Using Pluripotent Stem Cells

  15. Chapter

    Pages 177-191

    Reprogramming Towards Pancreatic β-Cells

  16. Chapter

    Pages 193-215

    Pancreatic Plasticity and Reprogramming: Novel Directions Towards Disease Therapy

  17. Chapter

    Pages 217-238

    Phenotype and Developmental Potential of Cardiomyocytes from Induced Pluripotent Stem Cells and Human Embryonic Stem Cells

  18. Chapter

    Pages 239-250

    The Generation of Disease-Specific Cell Lines and Their Use for Developing Drug Therapies

  19. Chapter

    Pages 251-264

    Advances in the Culture of Human Embryonic Stem Cells

  20. Chapter

    Pages 265-276

    Culture Adaptation of Pluripotent Stem Cells: Challenges and Opportunities

  21. Chapter

    Pages 277-278


  22. Back Matter

    Pages 279-332