In vivo NMR Imaging

Methods and Protocols

Editors:

ISBN: 978-1-61779-218-2 (Print) 978-1-61779-219-9 (Online)

Table of contents (36 protocols)

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  1. Front Matter

    Pages i-xiii

  2. Basics of MRI

    1. Front Matter

      Pages 1-1

    2. No Access

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      Pages 3-21

      Physical Basics of NMR

    3. No Access

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      Pages 23-43

      Spatial Encoding – Basic Imaging Sequences

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      Pages 45-67

      Basic Contrast Mechanisms

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      Pages 69-88

      Scanner Components

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      Pages 89-113

      Small Animal Preparation and Handling in MRI

  3. Special Techniques

    1. Front Matter

      Pages 115-115

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      Pages 117-138

      Cerebral Perfusion MRI in Mice

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      Pages 139-152

      High Field Diffusion Tensor Imaging in Small Animals and Excised Tissue

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      Pages 153-169

      The BOLD Effect

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      Pages 171-187

      Screening of CEST MR Contrast Agents

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      Pages 189-204

      Hyperpolarized Noble Gases as Contrast Agents

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      Pages 205-226

      Hyperpolarized Molecules in Solution

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      Pages 227-240

      MR Oximetry

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      Pages 241-252

      MRI Using Intermolecular Multiple-Quantum Coherences

  4. Brain Applications

    1. Front Matter

      Pages 253-253

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      Pages 255-275

      Experimental Stroke Research: The Contributions of In Vivo MRI

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      Pages 277-291

      Volumetry and Other Quantitative Measurements to Assess the Rodent Brain

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      Pages 293-308

      Models of Neurodegenerative Disease – Alzheimer’s Anatomical and Amyloid Plaque Imaging

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      Pages 309-335

      MRI in Animal Models of Psychiatric Disorders

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      Pages 337-351

      Spectroscopic Imaging of the Mouse Brain

  5. Spine Applications

    1. Front Matter

      Pages 353-353

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      Pages 355-383

      Spinal Cord – MR of Rodent Models

  6. Cardiovascular Applications

    1. Front Matter

      Pages 385-385

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      Pages 387-405

      Assessment of Global Cardiac Function

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