Tumor Models in Cancer Research

Editors:

ISBN: 978-1-60761-967-3 (Print) 978-1-60761-968-0 (Online)

Table of contents (26 chapters)

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  1. Front Matter

    Pages i-xiv

  2. Introduction

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-20

      Perspectives on the History and Evolution of Tumor Models

  3. Transplantable Syngeneic Rodent Tumors

    1. Front Matter

      Pages 21-21

    2. No Access

      Book Chapter

      Pages 23-41

      Murine L1210 and P388 Leukemias

    3. No Access

      Book Chapter

      Pages 43-78

      Transplantable Syngeneic Rodent Tumors: Solid Tumors in Mice

    4. No Access

      Book Chapter

      Pages 79-95

      B16 Murine Melanoma: Historical Perspective on the Development of a Solid Tumor Model

  4. Human Tumor Xenografts

    1. Front Matter

      Pages 97-97

    2. No Access

      Book Chapter

      Pages 99-124

      Human Tumor Xenograft Efficacy Models

    3. No Access

      Book Chapter

      Pages 125-166

      Imaging the Steps of Metastasis at the Macro and Cellular Level with Fluorescent Proteins in Real Time

    4. No Access

      Book Chapter

      Pages 167-193

      Patient-Derived Tumor Models and Explants

    5. No Access

      Book Chapter

      Pages 195-213

      The Pediatric Preclinical Testing Program

    6. No Access

      Book Chapter

      Pages 215-241

      Imaging Efficacy in Tumor Models

  5. Carcinogen-Induced Tumors

    1. Front Matter

      Pages 243-243

    2. No Access

      Book Chapter

      Pages 245-255

      Mammary Cancer in Rats

  6. Disease and Target-Specific Models

    1. Front Matter

      Pages 257-257

    2. No Access

      Book Chapter

      Pages 259-285

      Animal Models of Melanoma

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      Book Chapter

      Pages 287-305

      Experimental Animal Models for Investigating Renal Cell Carcinoma Pathogenesis and Preclinical Therapeutic Approaches

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      Book Chapter

      Pages 307-324

      Animal Models of Mesothelioma

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      Book Chapter

      Pages 325-351

      The Use of Mouse Models to Study Leukemia/Lymphoma and Assess Therapeutic Approaches

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      Book Chapter

      Pages 353-373

      Spontaneous Companion Animal (Pet) Cancers

  7. Genetically Engineered Mouse Models of Cancer

    1. Front Matter

      Pages 375-375

    2. No Access

      Book Chapter

      Pages 377-395

      Genetically Engineered Mouse Models of Pancreatic Ductal Adenocarcinoma

    3. No Access

      Book Chapter

      Pages 397-421

      Transgenic Adenocarcinoma of the Mouse Prostate: A Validated Model for the Identification and Characterization of Molecular Targets and The Evaluation of Therapeutic Agents

    4. No Access

      Book Chapter

      Pages 423-443

      The Utility of Transgenic Mouse Models for Cancer Prevention Research

  8. Metastasis Models

    1. Front Matter

      Pages 445-445

    2. No Access

      Book Chapter

      Pages 447-495

      Models for Evaluation of Targeted Therapies of Invasive and Metastatic Disease

  9. Normal Tissue Response Models

    1. Front Matter

      Pages 497-497

    2. No Access

      Book Chapter

      Pages 499-519

      Animal Models of Toxicities Caused by Anti-Neoplastic Therapy

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