Translational Stem Cell Research

Issues Beyond the Debate on the Moral Status of the Human Embryo


ISBN: 978-1-60761-958-1 (Print) 978-1-60761-959-8 (Online)

Table of contents (31 chapters)

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  1. Front Matter

    Pages i-xxvi

  2. Translational Stem Cell Research: What is Possible Today and What Still Remains to be Achieved?

    1. Front Matter

      Pages 1-1

    2. Chapter

      Pages 3-14

      Towards Clinical Application of Stem Cells in Neurodegenerative Disorders

    3. Chapter

      Pages 15-22

      Treating Cardiac Disorders with Stem Cells

    4. Chapter

      Pages 23-34

      Treating Diabetes

    5. Chapter

      Pages 35-43

      Treating Oncologic Disease

    6. Chapter

      Pages 45-53

      Clinical Application of Autologous Epithelial Stem Cells in Disorders of Squamous Epithelia

    7. Chapter

      Pages 55-63

      Towards a Cell Therapy for Muscular Dystrophy: Technical and Ethical Issues

    8. Chapter

      Pages 65-76

      Towards Modeling and Therapy of Genetic Diseases Using Pluripotent Stem Cells

    9. Chapter

      Pages 77-90

      Therapeutic Possibilities of Induced Pluripotent Stem Cells

    10. Chapter

      Pages 91-102

      Industrial Applications of Stem Cells

    11. Chapter

      Pages 103-110

      The Obstacles on the Road to Clinical Applications of Stem Cell-Based Therapies: What Has Been Done to Overcome These Obstacles and What Remains to Be Done?

  3. Translating Stem Cell Research Knowledge from Bench to Bedside: Ethical Issues

    1. Front Matter

      Pages 111-111

    2. Chapter

      Pages 113-124

      Translational Stem Cell Research and Animal Use: Examining Ethical Issues and Opportunities

    3. Chapter

      Pages 125-135

      Ethical Aspects of Stem Cell-Based Clinical Translation: Research, Innovation,and Delivering Unproven Interventions

    4. Chapter

      Pages 137-149

      Translational Stem Cell Research in Pediatrics: Ethical Issues

    5. Chapter

      Pages 151-166

      Experimental Stem Cell-Based Therapy in Pediatrics: A Fictional Case Study

  4. Creation of Human-Animal Entities for Translational Stem Cell Research: Scientific, Ethical and Regulatory Challenges

    1. Front Matter

      Pages 167-167

    2. Chapter

      Pages 169-191

      Creation of Human–Animal Entities for Translational Stem Cell Research: Scientific Explanation of Issues That Are Often Confused

    3. Chapter

      Pages 193-209

      Chimeras and Hybrids – How to Approach Multifaceted Research?

    4. Chapter

      Pages 211-221

      Chimeras + Hybrids = Chimbrids: Legal Aspects

  5. Stem Cell Banking for Translational Stem Cell Research or Stem Cell-Based Therapies

    1. Front Matter

      Pages 223-223

    2. Chapter

      Pages 225-236

      Stem Cell Banks: Reality, Roles and Challenges

    3. Chapter

      Pages 237-250

      Broad Consent

    4. Chapter

      Pages 251-264

      Banks, Repositories and Registries of Stem Cell Lines: The Challenges to Legal Regulation

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