Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma

Editors:

ISBN: 978-1-60761-432-6 (Print) 978-1-60761-433-3 (Online)

Table of contents (23 chapters)

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  1. Front Matter

    Pages i-xiv

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    Book Chapter

    Pages 1-7

    Introduction to Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma

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    Pages 9-18

    Diagnostic and Prognostic Biomarkers in Melanoma: Current State of Play

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    Pages 19-37

    Molecular Pathogenesis of Melanoma: Established and Novel Pathways

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    Pages 39-48

    Staging of Melanoma

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    Pages 49-67

    Clinical and Histopathological Parameters in Melanoma

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    Pages 69-77

    Genetic/Epigenetic Biomarkers: Distinction of Melanoma from Other Melanocytic Neoplasms

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    Pages 79-88

    mRNA Biomarkers in Melanoma

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    Pages 89-112

    Epigenetic Biomarkers in Melanoma

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    Pages 113-126

    MicroRNA Biomarkers in Melanoma

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    Pages 127-144

    MicroRNAs as Biomarkers and Therapeutic Targets in Melanoma

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    Pages 145-157

    Mitochondrial DNA Biomarkers in Melanoma

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    Pages 159-176

    Tissue-Based Protein Biomarkers in Melanoma: Immunohistochemistry: (A) Diagnosis

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    Pages 177-188

    Tissue-Based Protein Biomarkers in Melanoma: Immunohistochemistry: (B) Prognostication

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    Pages 189-194

    Tissue-Based Protein Biomarkers in Melanoma: Mass Spectrometry-Based Strategies

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    Pages 195-208

    Serological Biomarkers in Melanoma

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    Pages 209-226

    Molecular Markers of Lymph Node Disease in Melanoma

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    Pages 227-241

    Melanoma Cell Propagation: Cancer Stem Cell, Clonal Evolution and Interconversion Models of Tumorigenicity

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    Pages 243-246

    Surgical Management of Melanoma: Concept of Field Cancerization and Molecular Evaluation of Tissue Margins

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    Book Chapter

    Pages 247-263

    Chemotherapy for Melanoma

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    Book Chapter

    Pages 265-279

    Molecular-Targeted Therapy for Melanoma

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