Paraoxonases in Inflammation, Infection, and Toxicology


ISBN: 978-1-60761-349-7 (Print) 978-1-60761-350-3 (Online)

Table of contents (17 chapters)

  1. Front Matter

    Pages i-xv

  2. Chapter

    Pages 1-4

    ApoE Mimetic Peptide Reduces Plasma Lipid Hydroperoxide Content with a Concomitant Increase in HDL Paraoxonase Activity

  3. Chapter

    Pages 5-18

    Interrelationships Between Paraoxonase-1 and Monocyte Chemoattractant Protein-1 in the Regulation of Hepatic Inflammation

  4. Chapter

    Pages 19-27

    Biomarkers of Sensitivity and Exposure in Washington State Pesticide Handlers

  5. Chapter

    Pages 29-35

    Paraoxonase 1 Status as a Risk Factor for Disease or Exposure

  6. Chapter

    Pages 37-45

    Engineering Human PON1 in an E. coli Expression System

  7. Chapter

    Pages 47-60

    The Toxicity of Mixtures of Specific Organophosphate Compounds is Modulated by Paraoxonase 1 Status

  8. Chapter

    Pages 61-71

    Identification and Characterization of Biomarkers of Organophosphorus Exposures in Humans

  9. Chapter

    Pages 73-87

    Temporal and Tissue-Specific Patterns of Pon3 Expression in Mouse: In situ Hybridization Analysis

  10. Chapter

    Pages 89-97

    PON1 and Oxidative Stress in Human Sepsis and an Animal Model of Sepsis

  11. Chapter

    Pages 99-111

    Paraoxonase 1 Attenuates Human Plaque Atherogenicity: Relevance to the Enzyme Lactonase Activity

  12. Chapter

    Pages 113-127

    The Role of Paraoxonase 1 in the Detoxification of Homocysteine Thiolactone

  13. Chapter

    Pages 129-142

    Alteration of PON1 Activity in Adult and Childhood Obesity and Its Relation to Adipokine Levels

  14. Chapter

    Pages 143-151

    Anti-Inflammatory Properties of Paraoxonase-1 in Atherosclerosis

  15. Chapter

    Pages 153-166

    Paraoxonase 1 Interactions with HDL, Antioxidants and Macrophages Regulate Atherogenesis – A Protective Role for HDL Phospholipids

  16. Chapter

    Pages 167-172

    The Effect of HDL Mimetic Peptide 4F on PON1

  17. Chapter

    Pages 173-181

    The Contribution of High Density Lipoprotein Apolipoproteins and Derivatives to Serum Paraoxonase-1 Activity and Function

  18. Chapter

    Pages 183-193

    Paraoxonase 1, Quorum Sensing, and P. aeruginosa Infection: A Novel Model

  19. Back Matter

    Pages 195-211