Heart Failure

Bench to Bedside

Authors:

ISBN: 978-1-60761-146-2 (Print) 978-1-60761-147-9 (Online)

Table of contents (23 chapters)

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  1. Front Matter

    Pages i-xi

  2. Clinical, Physiology and Genetics Changes in Heart Failure

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-13

      Introduction to Heart Failure

    3. No Access

      Book Chapter

      Pages 15-21

      Cardiac Function in Heart Failure: The Role of Calcium Cycling

    4. No Access

      Book Chapter

      Pages 23-42

      Gene Profiling of the Failing Heart: Epigenetics

  3. Biochemical and Molecular Changes in Heart Failure

    1. Front Matter

      Pages 44-44

    2. No Access

      Book Chapter

      Pages 45-69

      Bioenergetics and Metabolic Changes in the Failing Heart

  4. The Mitochondrial Organelle and the Heart

    1. Front Matter

      Pages 72-72

    2. No Access

      Book Chapter

      Pages 73-106

      The Multidimensional Role of Mitochondria in Heart Failure

  5. Experimental Models of Heart Failure

    1. Front Matter

      Pages 108-108

    2. No Access

      Book Chapter

      Pages 109-127

      Animal Models of Heart Failure

  6. Signaling, Stress and Cellular Changes in Heart Failure

    1. Front Matter

      Pages 130-130

    2. No Access

      Book Chapter

      Pages 131-160

      Signaling Cascades in Heart Failure: From Cardiomyocytes Growth and Survival to Mitochondrial Signaling Pathways

    3. No Access

      Book Chapter

      Pages 161-169

      Cyclic Nucleotides Signaling (Second Messengers) and Control of Myocardial Function: Effects of Heart Failure

    4. No Access

      Book Chapter

      Pages 171-194

      Calcium Signaling: Receptors, Effectors, and Other Signaling Pathways

    5. No Access

      Book Chapter

      Pages 195-211

      Oxidative Stress and Heart Failure

    6. No Access

      Book Chapter

      Pages 213-231

      Cardiac Remodeling and Cell Death in Heart Failure

  7. Peripheral Changes and Co-morbid Conditions in Heart Failure

    1. Front Matter

      Pages 234-234

    2. No Access

      Book Chapter

      Pages 235-255

      Heart Failure and Changes at the Periphery: Vascular, Inflammation, Neurohormonal, and Renal Systems

    3. No Access

      Book Chapter

      Pages 257-270

      Comorbidities in Heart Failure

  8. Heart Failure in Children

    1. Front Matter

      Pages 272-272

    2. No Access

      Book Chapter

      Pages 273-295

      Mechanisms and Clinical Recognition and Management of Heart Failure in Infants and Children

    3. No Access

      Book Chapter

      Pages 297-312

      Mechanical Circulatory Support and Heart Transplantation in Children with Severe Refractory Heart Failure

  9. Aging and the Failing Heart

    1. Front Matter

      Pages 314-314

    2. No Access

      Book Chapter

      Pages 315-340

      Basic Mechanisms Mediating Cardiomyopathy and Heart Failure in Aging

    3. No Access

      Book Chapter

      Pages 341-349

      Heart Failure of Aging: Clinical Considerations

  10. Diagnostic Methodology in Heart Failure

    1. Front Matter

      Pages 352-352

    2. No Access

      Book Chapter

      Pages 353-363

      Diagnosis of Heart Failure: Evidence-Based Perspective

    3. No Access

      Book Chapter

      Pages 365-376

      “Omics” Application in Heart Failure: Novel Diagnostic and Prognostic Markers to Understand Pathophysiology and Find New Therapies

  11. Available and Forthcoming Therapies for Heart Failure

    1. Front Matter

      Pages 378-378

    2. No Access

      Book Chapter

      Pages 379-392

      Treatment of Chronic Heart Failure

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