High Throughput Screening

Methods and Protocols, Second Edition

Editors:

ISBN: 978-1-60327-257-5 (Print) 978-1-60327-258-2 (Online)

Table of contents (12 protocols)

  1. Front Matter

    Pages i-xii

  2. No Access

    Book Protocol

    Pages 1-32

    Design and Implementation of High-Throughput Screening Assays

  3. No Access

    Book Protocol

    Pages 33-54

    Creation of a Small High-Throughput Screening Facility

  4. No Access

    Book Protocol

    Pages 55-68

    Informatics in Compound Library Management

  5. No Access

    Book Protocol

    Pages 69-106

    Statistics and Decision Making in High-Throughput Screening

  6. No Access

    Book Protocol

    Pages 107-126

    Enzyme Assay Design for High-Throughput Screening

  7. No Access

    Book Protocol

    Pages 127-143

    Application of Fluorescence Polarization in HTS Assays

  8. No Access

    Book Protocol

    Pages 145-158

    Screening G Protein-Coupled Receptors: Measurement of Intracellular Calcium Using the Fluorometric Imaging Plate Reader

  9. No Access

    Book Protocol

    Pages 159-186

    High-Throughput Automated Confocal Microscopy Imaging Screen of a Kinase-Focused Library to Identify p38 Mitogen-Activated Protein Kinase Inhibitors Using the GE InCell 3000 Analyzer

  10. No Access

    Book Protocol

    Pages 187-208

    Recent Advances in Electrophysiology-Based Screening Technology and the Impact upon Ion Channel Discovery Research

  11. No Access

    Book Protocol

    Pages 209-223

    Automated Patch Clamping Using the QPatch

  12. No Access

    Book Protocol

    Pages 225-237

    High-Throughput Screening of the Cyclic AMP-Dependent Protein Kinase (PKA) Using the Caliper Microfluidic Platform

  13. No Access

    Book Protocol

    Pages 239-257

    Use of Primary Human Cells in High-Throughput Screens

  14. Back Matter

    Pages 259-268