National Institute of Allergy and Infectious Diseases, NIH

Frontiers in Research

ISBN: 978-1-934115-77-0 (Print) 978-1-59745-569-5 (Online)

Table of contents (54 chapters)

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  1. Front Matter

    Pages i-xviii

  2. Introduction

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      Pages 3-8

      National Institute of Allergy and Infectious Diseases (NIAID): An Overview

  3. Microbiology and Infectious Diseases

    1. Emerging and Re-Emerging Infections

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        Pages 13-17

        Biotools for Determining the Genetics of Susceptibility to Infectious Diseases and Expediting Research Translation Into Effective Countermeasures

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        Pages 19-23

        Spore Surface Components and Protective Immunity to Bacillus anthracis

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        Pages 25-36

        New Candidate Anthrax Pathogenic Factors

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        Pages 37-46

        Ehrlichiae and Ehrlichioses: Pathogenesis and Vector Biology

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        Pages 47-54

        Multiple Locus Variable Number Tandem Repeat (VNTR) Analysis (MLVA) of Brucella spp. Identifies Species-Specific Markers and Insights into Phylogenetic Relationships

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        Pages 55-63

        Expression of the MtrC-MtrD-MtrE Efflux Pump in Neisseria gonorrhoeae and Bacterial Survival in the Presence of Antimicrobials

      Tuberculosis

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        Pages 67-76

        What can Mycobacteriophages Tell Us About Mycobacterium tuberculosis?

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        Pages 77-81

        Clinical Mycobacterium tuberculosis Strains Differ in their Intracellular Growth in Human Macrophages

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        Pages 83-90

        Mechanisms of Latent Tuberculosis: Dormancy and Resuscitation of Mycobacterium tuberculosis

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        Pages 91-99

        Separating Latent and Acute Disease in the Diagnosis of Tuberculosis

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        Pages 101-106

        Mutant Selection Window Hypothesis: A Framework for Anti-mutant Dosing of Antimicrobial Agents

      Avian Influenza

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        Pages 109-113

        The NIAID Influenza Genome Sequencing Project

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        Pages 115-122

        Lessons From the 1918 Spanish Flu Epidemic in Iceland

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        Pages 123-129

        Control of Notifiable Avian Influenza Infections in Poultry

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        Pages 131-141

        Understanding the Complex Pathobiology of High Pathogenicity Avian Influenza Viruses in Birds

      Prophylactics and Therapeutics for Infectious Diseases

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        Pages 145-161

        Development of Prophylactics and Therapeutics Against the Smallpox and Monkeypox Biothreat Agents

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        Pages 163-177

        The Hierarchic Informational Technology for QSAR Investigations: Molecular Design of Antiviral Compounds

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        Pages 179-192

        Antivirals for Influenza: Novel Agents and Approaches

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        Pages 193-198

        Anti-Infectious Actions of Proteolysis Inhibitor ε-Aminocaproic Acid (ε-ACA)

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