Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy

Editors:

ISBN: 978-1-934115-29-9 (Print) 978-1-59745-474-2 (Online)

Table of contents (22 chapters)

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  1. Front Matter

    Pages i-xxi

  2. Sensitization via Membrane-Bound Receptors

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      Chapter

      Pages 3-11

      Sensitization of Epithelial Cancer Cells with Human Monoclonal Antibodies

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      Chapter

      Pages 13-27

      Targeting the Transferrin Receptor to Overcome Resistance to Anti-Cancer Agents

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      Chapter

      Pages 29-39

      Chemo-Immunosensitization of Resistant B-NHL as a Result of Rituximab (anti-CD20 mAb)-Mediated Inhibition of Cell Survival Signaling Pathways

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      Chapter

      Pages 41-49

      Agents that Regulate DR5 and Sensitivity to TRAIL

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      Chapter

      Pages 51-60

      Proteasome Inhibition: Potential for Sensitization of Immune Effector Mechanisms in Cancer

  3. Sensitization via Inhibition of Cell Survival Pathways (Excluding Apoptotic Signaling Pathways)

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      Chapter

      Pages 63-80

      Angiogenesis Inhibitors as Enabling Agents for the Chemotherapeutic Treatment of Metastatic Disease

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      Chapter

      Pages 81-114

      Targeting Survival Cascades Induced by Activation of Ras/Raf/MEK/ERK and PI3K/Akt Pathways to Sensitize Cancer Cells to Therapy

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      Chapter

      Pages 115-131

      Histone Deacetylase Inhibitors and Anticancer Activity

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      Chapter

      Pages 133-156

      Eicosanoids and Resistance of Cancer Cells to Chemotherapeutic Agents

  4. Sensitization via Transcription Factors

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      Chapter

      Pages 159-174

      The RKIP and STAT3 Axis in Cancer Chemotherapy: Opposites Attract

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      Chapter

      Pages 175-187

      Targeting Transcription Factors with Decoy Oligonucleotides: Modulation of the Expression of Genes Involved in Chemotherapy Resistance of Tumor Cells

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      Chapter

      Pages 189-202

      p53 Inhibitors as Cancer Sensitizing Agents

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      Chapter

      Pages 203-210

      Nitric Oxide—Induced Immunosensitization to Apoptosis by Fas-L and TRAIL

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      Chapter

      Pages 211-240

      Natural Agents That Can Sensitize Tumor Cells to Chemotherapy and Radiation Therapy

  5. Sensitization via Targeting Apoptotic Pathways

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      Chapter

      Pages 243-261

      Inhibitors of the Bcl-2 Protein Family as Sensitizers to Anticancer Agents

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      Chapter

      Pages 263-278

      Therapeutic Targeting of Apoptosis in Cancer

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      Chapter

      Pages 279-303

      Peptides and Peptidomimetics as Cancer Therapy Sensitizing Agents

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      Chapter

      Pages 305-325

      Non-Peptidic Mimetics as Cancer-Sensitizing Agents

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      Chapter

      Pages 327-335

      Sensitization of Cancer Cells to Cancer Therapies by Isoflavone and Its Synthetic Derivatives

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      Chapter

      Pages 337-362

      Antisense Oligonucleotides and siRNA as Specific Inhibitors of Gene Expression: Mechanisms of Action and Therapeutic Potential

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