Book 2008

Principles of Molecular Oncology

ISBN: 978-1-934115-25-1 (Print) 978-1-59745-470-4 (Online)

Table of contents (20 chapters)

  1. Front Matter

    Pages i-xix

  2. Chapter

    Pages 1-26

    Selecting the Right Targets for Cancer Therapy

  3. Chapter

    Pages 27-41

    Clinical Importance of Prognostic Factors

  4. Chapter

    Pages 43-84

    Genetic Markers in Sporadic Tumors

  5. Chapter

    Pages 85-105

    Genetic Markers in Breast Tumors with Hereditary Predisposition

  6. Chapter

    Pages 107-116

    Circulating Tumor Markers

  7. Chapter

    Pages 117-134

    Antibody-Based Proteomics Analysis of Tumor Cell Signaling Pathways

  8. Chapter

    Pages 135-152

    Gene Expression Arrays for Pathway Analysis in Cancer Research

  9. Chapter

    Pages 153-188

    Signaling Pathways in Cancer

  10. Chapter

    Pages 189-206

    Estrogen Receptor Pathways and Breast Cancer

  11. Chapter

    Pages 207-237

    Cyclin-Dependent Kinases and Their Regulators as Potential Targets for Anticancer Therapeutics

  12. Chapter

    Pages 239-256

    Angiogenesis Switch Pathways

  13. Chapter

    Pages 257-268

    Apoptosis Pathways and New Anticancer Agents

  14. Chapter

    Pages 269-279

    Genomic Instability, DNA Repair Pathways and Cancer

  15. Chapter

    Pages 281-291

    Epigenomics and Cancer

  16. Chapter

    Pages 293-306

    Harnessing the Power of Immunity to Battle Cancer: Much Ado about Nothing or All's Well That Ends Well?

  17. Chapter

    Pages 307-315

    Aurora Kinases: A New Target for Anticancer Drug Development

  18. Chapter

    Pages 317-365

    Emerging Molecular Therapies: Drugs Interfering With Signal Transduction Pathways

  19. Chapter

    Pages 367-382

    Suicide Gene Therapy

  20. Chapter

    Pages 383-390

    Genotypes That Predict Toxicity and Genotypes That Predict Efficacy of Anticancer Drugs

  21. Chapter

    Pages 391-398

    A Personal Account of the Chemoprevention of Breast Cancer: Possible or Not Possible?

  22. Back Matter

    Pages 399-418