Mechanisms of the Glaucomas

Disease Processes and Therapeutic Modalities

ISBN: 978-1-58829-956-7 (Print) 978-1-59745-373-8 (Online)

Table of contents (39 chapters)

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  1. Front Matter

    Pages I-XIX

  2. Epidemiology of Glaucoma

    1. Front Matter

      Pages 1-1

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      Book Chapter

      Pages 3-17

      Age and Racial Variation in the Prevalence of Open-Angle Glaucoma in the USA

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      Book Chapter

      Pages 19-33

      Epidemiology of and Risk Factors for Primary Open-Angle Glaucoma

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      Book Chapter

      Pages 35-47

      The Reykjavik Eye Study on Prevalence of Glaucoma in Iceland and IdentifiedRisk Factors

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      Pages 49-61

      Defined Glaucoma in Chinese Population

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      Pages 63-79

      The Wroclaw Epidemiological Study: Screening Possibilities of Glaucoma Detection

  3. Mechanisms of Intraocular Pressure Elevation in the Glaucomas

    1. Front Matter

      Pages 81-82

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      Book Chapter

      Pages 83-97

      Pretrabecular Mechanisms of Intraocular Pressure Elevation

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      Book Chapter

      Pages 99-116

      Glaucomatous Changes in the Trabecular Meshwork

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      Pages 117-138

      Trabecular Mechanisms of Intraocular Pressure Elevation

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      Book Chapter

      Pages 139-157

      Post-Trabecular Glaucomas with Elevated Episcleral Venous Pressure

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      Pages 159-165

      Angle-Closure Glaucomas Anterior (Pulling) Mechanisms

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      Pages 167-172

      Angle-Closure Glaucomas

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      Pages 173-187

      Angle-Closure Glaucomas

  4. Genetics of Glaucoma

    1. Front Matter

      Pages 189-189

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      Pages 191-203

      Genetics and Glaucoma Susceptibility

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      Pages 205-217

      Myocilin Mutations and Their Role in Open-Angle Glaucoma

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      Pages 219-231

      The Functional Role of Myocilin in Glaucoma

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      Pages 233-273

      Roles of CYP1B1, Optineurin, and WDR36 Gene Mutations in Glaucoma

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      Book Chapter

      Pages 275-288

      Genetic Association in the Open-Angle Glaucomas

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      Pages 289-307

      ApoE Polymorphisms and Severity of Open-Angle Glaucoma

  5. Molecular and Cellular Responses in the Eye to Glaucoma

    1. Front Matter

      Pages 309-309

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      Book Chapter

      Pages 311-327

      Changes in Aqueous Humor Dynamics with Age and Glaucoma

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      Book Chapter

      Pages 329-362

      Mechanosensitive Genes in the Trabecular Meshwork at Homeostasis

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