2009

Renal Cell Carcinoma

Molecular Targets and Clinical Applications

Editors:

ISBN: 978-1-58829-737-2 (Print) 978-1-59745-332-5 (Online)

Table of contents (25 chapters)

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  1. Front Matter

    Pages i-xvii

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    Book Chapter

    Pages 1-12

    Targeted Therapy for Metastatic Renal Cell Carcinoma: Overview

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    Book Chapter

    Pages 13-33

    Molecular Genetics in Inherited Renal Cell Carcinoma: Identification of Targets in the Hereditary Syndromes

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    Book Chapter

    Pages 35-48

    Molecular Targets in Renal Tumors: Pathologic Assessment

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    Book Chapter

    Pages 49-78

    Interferons and Interleukin-2: Molecular Basis of Activity and Therapeutic Results

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    Book Chapter

    Pages 79-97

    The Molecular Biology of Kidney Cancer and Its Clinical Translation into Treatment Strategies

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    Book Chapter

    Pages 99-118

    VEGF: Biologic Aspects and Clinical Approaches

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    Book Chapter

    Pages 119-149

    VEGF and PDGF Receptors: Biologic Relevance and Clinical Approaches to Inhibition

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    Book Chapter

    Pages 151-165

    Sunitinib and Axitinib in Renal Cell Carcinoma

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    Book Chapter

    Pages 167-187

    Sorafenib in Renal Cell Carcinoma

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    Book Chapter

    Pages 189-193

    Additional Tyrosine Kinase Inhibitors in Renal Cell Carcinoma

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    Book Chapter

    Pages 195-209

    Integrin α5β1 as a Novel Therapeutic Target in Renal Cancer

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    Book Chapter

    Pages 211-229

    Carbonic Anhydrase IX: Biology and Clinical Approaches

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    Book Chapter

    Pages 231-247

    Monoclonal Antibody G250 Recognizing Carbonic Anhydrase IX in Renal Cell Carcinoma: Biological and Clinical Studies

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    Book Chapter

    Pages 249-265

    Chemokines in Renal Cell Carcinoma: Implications for Tumor Angiogenesis and Metastasis

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    Book Chapter

    Pages 267-285

    PI3K/Akt/mTOR Pathway: A Growth and Proliferation Pathway

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    Book Chapter

    Pages 287-303

    EGFR and HER2: Relevance in Renal Cell Carcinoma

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    Book Chapter

    Pages 305-320

    Proteasome–NFκB Signaling Pathway: Relevance in RCC

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    Book Chapter

    Pages 321-334

    The Role of Hepatocyte Growth Factor Pathway Signaling in Renal Cell Carcinoma

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    Book Chapter

    Pages 335-346

    Smac/DIABLO: A Proapoptotic Molecular Target in Renal Cell Cancer

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    Book Chapter

    Pages 347-366

    EphA2: A Novel Target in Renal Cell Carcinoma

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