Acute Myelogenous Leukemia

Editors:

ISBN: 978-1-58829-621-4 (Print) 978-1-59745-322-6 (Online)

Table of contents (20 chapters)

  1. Front Matter

    Pages i-xiv

  2. Overview of AML

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-23

      Approaching the Treatment of AML from a Biological Perspective

  3. Molecular Foundations of AML Pathogenesis and Physiology

    1. Front Matter

      Pages 25-25

    2. No Access

      Book Chapter

      Pages 27-42

      Aberrant Transcription Factors in AML

    3. No Access

      Book Chapter

      Pages 43-70

      Myelodysplasia-Related AML

    4. No Access

      Book Chapter

      Pages 71-95

      Therapy-related AML

    5. No Access

      Book Chapter

      Pages 97-131

      The DNA Damage Response, DNA Repair, and AML

    6. No Access

      Book Chapter

      Pages 133-161

      Altered Apoptosis in AML

    7. No Access

      Book Chapter

      Pages 163-173

      Drug Resistance Transporters in AML

  4. Translating Biology into Clinical Application

    1. Front Matter

      Pages 175-175

    2. No Access

      Book Chapter

      Pages 177-192

      Impact of Cytogenetics on Clinical Outcome in AML

    3. No Access

      Book Chapter

      Pages 193-228

      APL: A Classic Tale of Bench to Bedside

  5. Molecular Therapeutics of AML: Selected Targeted Approaches

    1. Front Matter

      Pages 229-229

    2. No Access

      Book Chapter

      Pages 231-246

      Emerging Therapeutics for AML

    3. No Access

      Book Chapter

      Pages 247-261

      FLT3: A Prototype Receptor Tyrosine Kinase Target in AML

    4. No Access

      Book Chapter

      Pages 263-274

      Farnesyl Transferase Inhibitors in the Therapy of AML

    5. No Access

      Book Chapter

      Pages 275-291

      Modulating Gene Expression as a Therapeutic Approach in the Treatment of AML

    6. No Access

      Book Chapter

      Pages 293-312

      Differentiation Therapy in AML

    7. No Access

      Book Chapter

      Pages 313-327

      Stem Cell Transplantation for AML

    8. No Access

      Book Chapter

      Pages 329-341

      Tumor Vaccines in Leukemia

  6. Special Challenges

    1. Front Matter

      Pages 343-343

    2. No Access

      Book Chapter

      Pages 345-372

      Treatment, Outcomes, and Challenges of Newly Diagnosed AML in Children and Adolescents

    3. No Access

      Book Chapter

      Pages 373-384

      AML in Older Adults

    4. No Access

      Book Chapter

      Pages 385-398

      Dameshek Smiles: Molecular Clues to the Chronic Myeloproliferative Disorders Unmasked

    5. No Access

      Book Chapter

      Pages 399-415

      New Designs for Clinical Trials

  7. Back Matter

    Pages 417-426