Genomics in Endocrinology

DNA Microarray Analysis in Endocrine Health and Disease


ISBN: 978-1-58829-651-1 (Print) 978-1-59745-309-7 (Online)

Table of contents (15 chapters)

  1. Front Matter

    Pages I-XI

  2. Introduction

    1. Front Matter

      Pages 1-1

    2. Chapter

      Pages 3-22

      Microarray-based Gene Expression Analysis of Endocrine Systems: Principles of Experimental Design and Interpretation

  3. Hormone Action and Molecular Mechanisms

    1. Front Matter

      Pages 23-23

    2. Chapter

      Pages 25-39

      Gene Expression Profiles and Transcription Factors Involved in Parathyroid Hormone Signaling in Osteoblastic Cells

    3. Chapter

      Pages 41-66

      Analysis of Growth Hormone Effects on Hepatic Gene Expression in Hypophysectomized Rats

    4. Chapter

      Pages 67-82

      Gene Expression Profiling in Leiomyoma in Response to GnRH Therapy and TGF-β

    5. Chapter

      Pages 83-113

      Gene Profiling Analysis of Androgen Receptor Mediated Function

    6. Chapter

      Pages 115-129

      Interrogating Estrogen Receptor α Signaling in Breast Cancer by Chromatin Immunoprecipitation Microarrays

    7. Chapter

      Pages 131-143

      Gene Expression Analysis of the Adrenal Cortex in Health and Disease

  4. Endocrine Producing Tissues

    1. Front Matter

      Pages 145-145

    2. Chapter

      Pages 147-164

      DNA Microarray Analysis of Human Uterine Decidualization

    3. Chapter

      Pages 165-183

      Large-scale DNA Microarray Data Analysis Reveals Glucocorticoid Receptor-mediated Breast Cancer Cell Survival Pathways

    4. Chapter

      Pages 185-205

      Application of Microarrays for Gene Transcript Analysis in Type 2 Diabetes

    5. Chapter

      Pages 207-215

      DNA Microarray Analysis of Effects of TSH, Iodide, Cytokines, and Therapeutic Agents on Gene Expression in Cultured Human Thyroid Follicles

  5. Diseases of Hormonal Systems

    1. Front Matter

      Pages 217-217

    2. Chapter

      Pages 219-237

      Genomics and Polycystic Ovary Syndrome (PCOS): The Use of Microarray Analysis to Identify New Candidate Genes

    3. Chapter

      Pages 239-262

      Microarray Analysis of Alterations Induced by Obesity in White Adipose Tissue Gene Expression Profiling

    4. Chapter

      Pages 263-270

      Novel Molecular Signaling and Classification of Human Clinically Nonfunctioning Pituitary Adenomas Identified by Microarray and Reverse Transcription-Quantitative Polymerase Chain Reaction

    5. Chapter

      Pages 271-281

      Gene Expression Studies of Prostate Hyperplasia in Prolactin Transgenic Mice

  6. Back Matter

    Pages 283-288