Transforming Growth Factor-β in Cancer Therapy, Volume II

Cancer Treatment and Therapy

Editors:

ISBN: 978-1-58829-715-0 (Print) 978-1-59745-293-9 (Online)

Table of contents (46 chapters)

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  1. Front Matter

    Pages i-xxvi

  2. Transforming Growth Factor-β In Developing and Advanced Cancers

    1. Front Matter

      Pages 1-1

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      Book Chapter

      Pages 3-19

      Transforming Growth Factor-β Signaling in Pancreas Development and Pancreatic Disease

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      Book Chapter

      Pages 21-32

      Role of Transforming Growth Factor-β in the Pathogenesis of Human Head and Neck Squamous Cell Carcinoma

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      Book Chapter

      Pages 33-49

      TGF-β, Smads and Cervical Cancer

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      Pages 51-62

      TGF-β Signaling and Biglycan in Pancreatic Cancer

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      Book Chapter

      Pages 63-78

      TGF-β Signaling in Endometrial Cancer

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      Book Chapter

      Pages 79-93

      TGF-β Ligands, TGF-β Receptors, and Lung Cancer

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      Book Chapter

      Pages 95-123

      Role of TGF-β in Osteolytic Bone Metastases

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      Book Chapter

      Pages 125-132

      Hormonal Regulation of Transforming Growth Factor-β in Breast Cancer

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      Book Chapter

      Pages 133-140

      TGF-β and Progression of Esophageal Cancer

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      Book Chapter

      Pages 141-151

      TGF-β and HER2/ErbB2 and Breast Cancer Progression

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      Book Chapter

      Pages 153-166

      TGF-β Dependent T-Cell Regulation in Colitis and Colon Cancer

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      Book Chapter

      Pages 167-179

      Role of Transforming Growth Factor-β in the Kidney — Physiology and Pathology

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      Book Chapter

      Pages 181-202

      Perturbations of TGF-β Signaling in Leukocytes as Drivers of Leukemogenesis and Epithelial Tumorigenesis

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      Book Chapter

      Pages 203-218

      Transforming Growth Factor-β in Brain Functions and Dysfunctions

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      Book Chapter

      Pages 219-227

      Inhibition of TGF-β Signaling in Multiple Myeloma and Its Bone Marrow Microenvironment

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      Book Chapter

      Pages 229-246

      Key Roles of TGF-β and Smad3 in Prostate Cancer

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      Book Chapter

      Pages 247-261

      Smad Signaling in Leukemic Growth and Differentiation: Crosstalk Between Smad and Multiple Pathways Through Activation of the TGF-β Type I Receptor

  3. Transforming Growth Factor-β in Cancer Treatment and Therapy

    1. Front Matter

      Pages 263-263

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      Book Chapter

      Pages 265-284

      High-Throughput Screening of Protein Interaction Networks in the TGFβ Interactome: Understanding the Signaling Mechanisms Driving Tumor Progression

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      Book Chapter

      Pages 285-307

      Tumor Suppressor and Pro-progression Roles for TGF-β in Breast Cancer

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      Book Chapter

      Pages 309-320

      Tumor Suppressors p53 and TGFβ Converge to Regulate the Alpha-Fetoprotein Oncodevelopmental Tumor Marker

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