Book 2005

Molecular Neurosurgery With Targeted Toxins


ISBN: 978-1-58829-199-8 (Print) 978-1-59259-896-0 (Online)

Table of contents (13 chapters)

  1. Front Matter

    Pages i-xi

  2. Chapter

    Pages 1-8

    Introduction to Molecular Neurosurgery

  3. Chapter

    Pages 9-29

    Ribosome-Inactivating Proteins

  4. Chapter

    Pages 31-58

    Biochemical, Physiological, and Behavioral Characterizations of the Cholinergic Basal Forebrain Lesion Produced by 192 IgG-Saporin

  5. Chapter

    Pages 59-86

    Basal Forebrain Cholinergic Lesion by 192 IgG-Saporin

  6. Chapter

    Pages 87-100

    192 IgG-Saporin-Induced Partial Cortical Cholinergic Deafferentation as a Model for Determining the Interactions Between Brain Aging and Neurodevelopmental Defects in the Cortical Cholinergic Input System

  7. Chapter

    Pages 101-142

    Exploring the Role of Acetylcholine in Primate Cognition Using Me20.4 IgG-Saporin

  8. Chapter

    Pages 143-180

    Cortical Cholinergic Deafferentation Induces Aβ Deposition

  9. Chapter

    Pages 181-218

    Chemical Dissection of Brain Glucoregulatory Circuitry

  10. Chapter

    Pages 219-233

    Cardiovascular Deficits After Lesions of C1 Adrenergic Neurons With a Saporin-Based Immunotoxin

  11. Chapter

    Pages 235-248

    Saporin Conjugates and Pain

  12. Chapter

    Pages 249-264

    The Use of Saporin Conjugates to Dissect Neurons Responsible for Sleep and Wakefulness

  13. Chapter

    Pages 265-291

    Isolectin IB4-Mediated Cytotoxic Targeting of Sensory Neurons

  14. Chapter

    Pages 293-306

    B Fragment of Cholera Toxin Conjugated to Saporin

  15. Back Matter

    Pages 307-311