Volume 137 1987

DNA—Ligand Interactions

From Drugs to Proteins

Editors:

ISBN: 978-1-4684-5385-0 (Print) 978-1-4684-5383-6 (Online)

Table of contents (20 chapters)

  1. Front Matter

    Pages i-x

  2. DNA Structure and Interaction with Small Molecules

    1. No Access

      Book Chapter

      Pages 1-21

      DNA Structure: Current Results from Single Crystal X-Ray Diffraction Studies

    2. No Access

      Book Chapter

      Pages 23-43

      One- and Two-Dimensional NMR Studies of the Structures of Simple Sequence DNAs

    3. No Access

      Book Chapter

      Pages 45-62

      The Major and Minor Grooves of the DNA Helix as Conduits for Information Transfer

    4. No Access

      Book Chapter

      Pages 63-83

      Unusual DNA Structures and Gene Regulation

    5. No Access

      Book Chapter

      Pages 85-104

      Specificity and Dynamics of Protein-Nucleic Acid Interactions

    6. No Access

      Book Chapter

      Pages 105-112

      DNA and its Counterions: Metal Ions, Amino Acids, Histones and Protamines

    7. No Access

      Book Chapter

      Pages 113-126

      Dynamic Aspects of Antibiotic-DNA Interaction

    8. No Access

      Book Chapter

      Pages 127-140

      Specific Gene Regulation by Oligodeoxynucleotides Covalently Linked to Intercalating Agents

    9. No Access

      Book Chapter

      Pages 141-157

      Pharmacology of DNA Binding Drugs

  3. DNA — Protein Interactions: Repressor — Operator Systems

    1. No Access

      Book Chapter

      Pages 159-171

      On the Nature and Specificity of DNA-Protein Interactions in the Regulation of Gene Expression

    2. No Access

      Book Chapter

      Pages 173-182

      Searching for the Code of Ideal Protein-DNA-Recognition

    3. No Access

      Book Chapter

      Pages 183-184

      trp Repressor, A Crystallographic Study of Allostery in Genetic Regulation

    4. No Access

      Book Chapter

      Pages 185-189

      Structural Studies of Three DNA Binding Proteins: Catabolite Gene Activator Protein, Resolvase, and the Klenow Fragment of DNA Polymerase I

    5. No Access

      Book Chapter

      Pages 191-215

      A Two-Dimensional NMR Study of the Complex of lac Repressor Headpiece with a 14 Base Pair lac Operator Fragment

  4. DNA — Protein Interactions: Methylation and Restriction Enzymes

    1. No Access

      Book Chapter

      Pages 217-224

      DNA Methylation and Mismatch Repair: Molecular Specificities

    2. No Access

      Book Chapter

      Pages 225-237

      Recognition of DNA Sequences by Restriction Endonucleases

    3. No Access

      Book Chapter

      Pages 239-250

      Mechanism and Specificity of two Restriction Enzymes, CauI and CauII, that Recognize Asymmetrical DNA Sequences

    4. No Access

      Book Chapter

      Pages 251-256

      Structure of the DNA-EcoRI Endonuclease Recognition Complex

  5. Outlook: DNA-Protein Interactions of Complex Systems

    1. No Access

      Book Chapter

      Pages 257-267

      Antibodies to Nucleic Acids

    2. No Access

      Book Chapter

      Pages 269-273

      Summary and Conclusions

  6. Back Matter

    Pages 275-290