Targeted Cancer Treatment in Silico

Small Molecule Inhibitors and Oncolytic Viruses

Authors:

ISBN: 978-1-4614-8300-7 (Print) 978-1-4614-8301-4 (Online)

Table of contents (15 chapters)

  1. Front Matter

    Pages i-xv

  2. No Access

    Book Chapter

    Pages 1-7

    Background and Scope of the Book

  3. Treatment of cancer with small molecule inhibitors

    1. Front Matter

      Pages 9-9

    2. No Access

      Book Chapter

      Pages 11-17

      An Introduction to Small Molecule Inhibitors and Chronic Myeloid Leukemia

    3. No Access

      Book Chapter

      Pages 19-33

      Basic Dynamics of Chronic Myeloid Leukemia During Imatinib Treatment

    4. No Access

      Book Chapter

      Pages 35-58

      Stochastic Modeling of Cellular Growth, Treatment, and Resistance Generation

    5. No Access

      Book Chapter

      Pages 59-72

      Evolutionary Dynamics of Drug Resistant Mutants in Targeted Treatment of CML

    6. No Access

      Book Chapter

      Pages 73-88

      Effect of Cellular Quiescence on the Evolution of Drug Resistance in CML

    7. No Access

      Book Chapter

      Pages 89-106

      Combination Therapies: Short-Term Versus Long-Term Strategies

    8. No Access

      Book Chapter

      Pages 107-117

      Cross Resistance: Treatment and Modeling

    9. No Access

      Book Chapter

      Pages 119-136

      Mathematical Modeling of Cyclic Cancer Treatments

  4. Treatment of cancer with oncolytic viruses

    1. Front Matter

      Pages 137-137

    2. No Access

      Book Chapter

      Pages 139-146

      Introduction to Oncolytic Viruses

    3. No Access

      Book Chapter

      Pages 147-156

      Basic Dynamics of Oncolytic Viruses

    4. No Access

      Book Chapter

      Pages 157-170

      Mitotic Virus Transmission and Immune Responses

    5. No Access

      Book Chapter

      Pages 171-194

      Axiomatic Approaches to Oncolytic Virus Modeling

    6. No Access

      Book Chapter

      Pages 195-213

      Spatial Oncolytic Virus Dynamics

    7. No Access

      Book Chapter

      Pages 215-224

      Oncolytic Viruses and the Eradication of Drug-Resistant Tumor Cells

  5. Back Matter

    Pages 225-227