Book 2013

Complex Systems and Computational Biology Approaches to Acute Inflammation

Editors:

ISBN: 978-1-4614-8007-5 (Print) 978-1-4614-8008-2 (Online)

Table of contents (15 chapters)

  1. Front Matter

    Pages i-xi

  2. No Access

    Chapter

    Pages 1-7

    An Overview of the Translational Dilemma and the Need for Translational Systems Biology of Inflammation

  3. Complex Systems Methods and Applications

    1. Front Matter

      Pages 9-9

    2. No Access

      Chapter

      Pages 11-28

      Translational Equation-Based Modeling

    3. No Access

      Chapter

      Pages 29-49

      Agent-Based Modeling in Translational Systems Biology

    4. No Access

      Chapter

      Pages 51-77

      Analysis of Heart Rate Variability

    5. No Access

      Chapter

      Pages 79-99

      Analysis of Ventilatory Pattern Variability

  4. Translational Modeling of Sepsis and Trauma

    1. Front Matter

      Pages 101-101

    2. No Access

      Chapter

      Pages 103-124

      Disorder of Systemic Inflammation in Sepsis and Trauma: A Systems Perspective

    3. No Access

      Chapter

      Pages 125-141

      Multiscale Equation-Based Models: Insights for Inflammation and Physiological Variability

    4. No Access

      Chapter

      Pages 143-157

      Integrating Data-Driven and Mechanistic Models of the Inflammatory Response in Sepsis and Trauma

    5. No Access

      Chapter

      Pages 159-170

      In Silico Trials and Personalized Therapy for Sepsis and Trauma

  5. Translational Modeling of Wound Healing

    1. Front Matter

      Pages 171-171

    2. No Access

      Chapter

      Pages 173-183

      Disorder of Localized Inflammation in Wound Healing: A Systems Perspective

    3. No Access

      Chapter

      Pages 185-207

      Equation-Based Models of Wound Healing and Collective Cell Migration

    4. No Access

      Chapter

      Pages 209-228

      Agent-Based Models of Wound Healing

  6. Translational Modeling of Host-Pathogen Interactions

    1. Front Matter

      Pages 229-229

    2. No Access

      Chapter

      Pages 231-264

      Modeling Host–Pathogen Interactions in Necrotizing Enterocolitis

    3. No Access

      Chapter

      Pages 265-279

      Modeling Host–Vector–Pathogen Immuno-inflammatory Interactions in Malaria

  7. Future Perspectives: Translation to Implementation

    1. Front Matter

      Pages 281-281

    2. No Access

      Chapter

      Pages 283-287

      The Rationale and Implementation of Translational Systems Biology as a New Paradigm for the Study of Inflammation

  8. Back Matter

    Pages 289-291