Cell Death Signaling in Cancer Biology and Treatment


ISBN: 978-1-4614-5846-3 (Print) 978-1-4614-5847-0 (Online)
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Table of contents (14 chapters)

  1. Front Matter

    Pages iii-xvi

  2. Book Chapter

    Pages 1-34

    Defective Apoptosis Signaling in Cancer

  3. Book Chapter

    Pages 35-51

    The Warburg Effect and Beyond: Metabolic Dependencies for Cancer Cells

  4. Book Chapter

    Pages 53-86

    Emerging Opportunities for Targeting the Tumor–Stroma Interactions for Increasing the Efficacy of Chemotherapy

  5. Book Chapter

    Pages 87-116

    The Role of Autophagy in Drug Resistance and Potential for Therapeutic Targeting

  6. Book Chapter

    Pages 117-136

    MicroRNAs in Cell Death and Cancer

  7. Book Chapter

    Pages 137-180

    Targeting DNA Repair Pathways for Cancer Therapy

  8. Book Chapter

    Pages 181-203

    Molecular Chaperones and How Addiction Matters in Cancer Therapy

  9. Book Chapter

    Pages 205-229

    Sphingolipid Metabolism and Signaling as a Target for Cancer Treatment

  10. Book Chapter

    Pages 231-253

    Leading Small Molecule Inhibitors of Anti-Apoptotic Bcl-2 Family Members

  11. Book Chapter

    Pages 255-279

    SMAC IAP Addiction in Cancer

  12. Book Chapter

    Pages 281-301

    Harnessing Death Receptor Signaling for Cancer Treatment

  13. Book Chapter

    Pages 303-329

    Proteasome Inhibition as a Novel Strategy for Cancer Treatment

  14. Book Chapter

    Pages 331-372

    New Agents and Approaches for Targeting the RAS/RAF/MEK/ERK and PI3K/AKT/mTOR Cell Survival Pathways

  15. Book Chapter

    Pages 373-399

    Activation of Immune-Mediated Tumor Cell Death by Chemotherapy

  16. Back Matter

    Pages 401-405