The Immunological Barriers to Regenerative Medicine

Editors:

ISBN: 978-1-4614-5479-3 (Print) 978-1-4614-5480-9 (Online)

Table of contents (16 chapters)

  1. Front Matter

    Pages i-xiii

  2. The Immunogenicity of Stem Cells

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-36

      Mechanisms of Immune Rejection of Stem Cell-Derived Tissues: Insights From Organ Transplantation

    3. No Access

      Book Chapter

      Pages 37-48

      The Immunogenicity of Embryonic Stem Cells and Their Differentiated Progeny

    4. No Access

      Book Chapter

      Pages 49-67

      Interaction of Embryonic Stem Cells with the Immune System

    5. No Access

      Book Chapter

      Pages 69-76

      The Role of NK Cells and T Cells in the Rejection of Embryonic Stem Cell-Derived Tissues

    6. No Access

      Book Chapter

      Pages 77-94

      Mitigating the Risk of Immunogenicity in the Pursuit of Induced Pluripotency

    7. No Access

      Book Chapter

      Pages 95-108

      Thymic Involution: A Barrier or Opportunity for Cell Replacement Therapy?

  3. Strategies for Overcoming Rejection of Stem Cell Grafts

    1. Front Matter

      Pages 109-109

    2. No Access

      Book Chapter

      Pages 111-128

      Construction of Human Embryonic Stem Cell Banks: Prospects for Tissue Matching

    3. No Access

      Book Chapter

      Pages 129-146

      Generation of Histocompatible Tissues via Parthenogenesis

    4. No Access

      Book Chapter

      Pages 147-173

      Prospects for Designing ‘Universal’ Stem Cell Lines

    5. No Access

      Book Chapter

      Pages 175-197

      The Immunosuppressive Properties of Adult Stem Cells: Mesenchymal Stem Cells as a Case Study

  4. Induction of Immunological Tolerance

    1. Front Matter

      Pages 199-199

    2. No Access

      Book Chapter

      Pages 201-223

      The Immunogenicity of Stem Cells and Thymus-Based Strategies to Minimise Immune Rejection

    3. No Access

      Book Chapter

      Pages 225-255

      The Induction of Mixed Chimerism Using ES Cell-Derived Hematopoietic Stem Cells

    4. No Access

      Book Chapter

      Pages 257-278

      Prospects for the Induction of Transplant Tolerance Using Dendritic Cells

    5. No Access

      Book Chapter

      Pages 279-295

      Strategies for the Induction of Tolerance with Monoclonal Antibodies

    6. No Access

      Book Chapter

      Pages 297-311

      Induction of Immunological Tolerance to Transgene Products

    7. No Access

      Book Chapter

      Pages 313-329

      Addressing the Challenge of Autoimmunity in the Treatment of Diabetes with Stem Cells

  5. Back Matter

    Pages 331-334