2013

Advances in Biology and Therapy of Multiple Myeloma

Volume 1: Basic Science

Editors:

ISBN: 978-1-4614-4665-1 (Print) 978-1-4614-4666-8 (Online)

Table of contents (16 chapters)

  1. Front Matter

    Pages i-x

  2. Myeloma Molecular Pathways and Cell Signaling

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-24

      Genomic Strategies Determining Progression from MGUS to Multiple Myeloma

    3. No Access

      Book Chapter

      Pages 25-39

      Prognostic Implication of Genetic Changes (Cytogenetics, and FISH, Gains and Losses of DNA by SNP Array and aCGH) in Risk Stratification in Myeloma

    4. No Access

      Book Chapter

      Pages 41-63

      Advances in Multiple Myeloma Gene-Expression Profiling

    5. No Access

      Book Chapter

      Pages 65-84

      Growth Factors in Multiple Myeloma

    6. No Access

      Book Chapter

      Pages 85-95

      Role of Wnt Signaling Pathways in Multiple Myeloma Pathogenesis

    7. No Access

      Book Chapter

      Pages 97-116

      The mTOR Pathway in Multiple Myeloma

    8. No Access

      Book Chapter

      Pages 117-138

      Jak/STAT Signaling in the Pathogenesis and Treatment of Multiple Myeloma

  3. Myeloma Microenvironment

    1. Front Matter

      Pages 139-139

    2. No Access

      Book Chapter

      Pages 141-168

      The Bone Marrow Microenvironment: Novel Targets to Circumvent Minimal Residual Disease and Drug Resistance in Multiple Myeloma

    3. No Access

      Book Chapter

      Pages 169-185

      Osteoclasts: Potential Target for Blocking Microenvironmental Support of Myeloma

    4. No Access

      Book Chapter

      Pages 187-202

      Targeting the BAFF/APRIL Cytokine Network in Multiple Myeloma

    5. No Access

      Book Chapter

      Pages 203-214

      Role of Osteoblast in Myeloma Pathology

    6. No Access

      Book Chapter

      Pages 215-239

      Migration and Homing in Multiple Myeloma

    7. No Access

      Book Chapter

      Pages 241-254

      Genes and Proteins of Myeloma Endothelial Cells to Search Specific Targets of the Tumor Vasculature

    8. No Access

      Book Chapter

      Pages 255-282

      Epigenetic Regulation of Myeloma Within Its Bone Marrow Microenvironment

    9. No Access

      Book Chapter

      Pages 283-299

      Targeting Multiple Myeloma Tumor Angiogenesis: Focus on VEGF

    10. No Access

      Book Chapter

      Pages 301-312

      Novel In Vivo Models in Myeloma

  4. Back Matter

    Pages 313-319