Book 2013


A Key Link between Metabolism and Brain Activity


ISBN: 978-1-4614-3902-8 (Print) 978-1-4614-3903-5 (Online)

Table of contents (29 chapters)

previous Page of 2
  1. Front Matter

    Pages i-xvi

  2. Introduction

    1. Front Matter

      Pages 1-1

    2. Chapter

      Pages 3-19

      Adenosine and Metabolism—A Brief Historical Note

  3. Molecular biology, pharmacology, and cell biology of adenosine

    1. Front Matter

      Pages 21-21

    2. Chapter

      Pages 23-54

      Adenosine Metabolism, Adenosine Kinase, and Evolution

    3. Chapter

      Pages 55-70

      Adenosine and Energy Metabolism—Relationship to Brain Bioenergetics

    4. Chapter

      Pages 71-85

      Adenosine and Autocrine Metabolic Regulation of Neuronal Activity

    5. Chapter

      Pages 87-107

      Physiologic and Metabolic Regulation of Adenosine: Mechanisms

    6. Chapter

      Pages 109-129

      The Double-Edged Sword: Gaining Adenosine at the Expense of ATP. How to Balance the Books

    7. Chapter

      Pages 131-156

      Downstream Pathways of Adenosine

    8. Chapter

      Pages 157-177

      Astrocytic ATP Release

    9. Chapter

      Pages 179-197

      Role of Striatal A2A Receptor Subpopulations in Neurological Disorders

  4. Adenosine function and dysfunction in brain health and disease

    1. Front Matter

      Pages 199-199

    2. Chapter

      Pages 201-212

      Sleep and Adenosine: Human Studies

    3. Chapter

      Pages 213-232

      Adenosine and Other Purinergic Products in Circadian Timing

    4. Chapter

      Pages 233-251

      Adenosine in the Immune System

    5. Chapter

      Pages 253-272

      The Bioenergetic Network of Adenosine in Hibernation, Sleep, and Thermoregulation

    6. Chapter

      Pages 273-306

      Adenosine and Stroke

    7. Chapter

      Pages 307-322

      The Many Roles of Adenosine in Traumatic Brain Injury

    8. Chapter

      Pages 323-342

      Therapeutic Perspectives of Adenosine Receptor Compounds in Functional Restitution After Spinal Cord Injury

    9. Chapter

      Pages 343-360

      Adenosine and Pain

    10. Chapter

      Pages 361-384

      Symptomatic and Neuroprotective Effects of A2A Receptor Antagonists in Parkinson’s Disease

    11. Chapter

      Pages 385-407

      Adenosine Receptors and Alzheimer’s Disease

    12. Chapter

      Pages 409-434

      Adenosine Receptors in Huntington’s Disease

previous Page of 2