2012

Renal Cell Carcinoma

Translational Biology, Personalized Medicine, and Novel Therapeutic Targets

Editors:

ISBN: 978-1-4614-2399-7 (Print) 978-1-4614-2400-0 (Online)

Table of contents (15 chapters)

  1. Front Matter

    Pages i-xi

  2. Biology of Renal Cell Carcinoma

    1. Front Matter

      Pages 1-1

    2. No Access

      Book Chapter

      Pages 3-25

      The Genetic Basis of Kidney Cancer and Implications for Targeted Therapies

    3. No Access

      Book Chapter

      Pages 27-47

      Molecular Biology of Clear Cell Renal Carcinoma

    4. No Access

      Book Chapter

      Pages 49-68

      HIF Biology in RCC: Implications for Signaling, Disease Progression, and Treatment

    5. No Access

      Book Chapter

      Pages 69-89

      Tissue Biomarkers in Renal Cell Carcinoma: Intermediate Endpoints in the Selection of Targeted Agents for RCC

    6. No Access

      Book Chapter

      Pages 91-111

      Molecular Characterization of Renal Cell Carcinoma

  3. Current and Future Molecular Targets for RCC

    1. Front Matter

      Pages 113-113

    2. No Access

      Book Chapter

      Pages 115-133

      Targeting the VEGF Pathway in Renal Cell Carcinoma

    3. No Access

      Book Chapter

      Pages 135-160

      Angiopoietins and Other Non-VEGF Antiangiogenic Targets in Advanced Renal Cell Carcinoma

    4. No Access

      Book Chapter

      Pages 161-191

      Research Translation and Personalized Medicine

    5. No Access

      Book Chapter

      Pages 193-211

      Epigenetic Targeting and Histone Deacetylase Inhibition in RCC

    6. No Access

      Book Chapter

      Pages 213-238

      C-MET as a Novel Target for the Treatment of Renal Cell Carcinoma

    7. No Access

      Book Chapter

      Pages 239-252

      Characterizing and Modulating the Tumor Microenvironment in Renal Cell Carcinoma: Potential Therapeutic Strategies

    8. No Access

      Book Chapter

      Pages 253-270

      Carbonic Anhydrase IX: Its Role as a Biomarker, Diagnostic, and Therapeutic Target in Renal Cell Carcinoma

    9. No Access

      Book Chapter

      Pages 271-282

      Presurgical Therapy for Renal Cell Carcinoma and Implications for Window-of-Opportunity Trials

    10. No Access

      Book Chapter

      Pages 283-303

      Mechanisms of Resistance to VEGF-Directed Therapy and Implications for Future Trial Design

    11. No Access

      Book Chapter

      Pages 305-322

      Vaccine-Based Immunotherapy and Targeting the Tumor Microenvironment in Renal Cell Carcinoma

  4. Back Matter

    Pages 323-327