2014

Molecular Biology of Valvular Heart Disease

Editors:

ISBN: 978-1-4471-6349-7 (Print) 978-1-4471-6350-3 (Online)

Table of contents (17 chapters)

  1. Front Matter

    Pages i-xvii

  2. No Access

    Book Chapter

    Pages 1-12

    Calcific Aortic Valve Disease: The Role of the Stem Cell Niche

  3. No Access

    Book Chapter

    Pages 13-20

    In Vitro Cell Culture Model of Calcification: Molecular Regulation of Myofibroblast Differentiation to an Osteoblast Phenotype

  4. No Access

    Book Chapter

    Pages 21-25

    Aortic Valve Apoptosis, Cell Proliferation and Atherosclerosis in Experimental Hypercholesterolemia

  5. No Access

    Book Chapter

    Pages 27-33

    Experimental Model of Aortic Valve Calcification to Induce Osteoblast Differentiation

  6. No Access

    Book Chapter

    Pages 35-40

    Development of an Experimental Model of Mitral Valve Regurgitation via Hypertrophic Chondrocytes

  7. No Access

    Book Chapter

    Pages 41-47

    Testing Drug Eluting Paclitaxel Balloon Valvuloplasty in an Experimental Model of Aortic Stenosis

  8. No Access

    Book Chapter

    Pages 49-54

    Ex Vivo Model for Bioprosthetic Valve Calcification via Stem Cell Differentiation to Bone

  9. No Access

    Book Chapter

    Pages 55-60

    Experimental Hypercholesterolemia in Genetic ApoE−/−/Lrp5−/− Mice: Proof of Principle

  10. No Access

    Book Chapter

    Pages 61-65

    Wnt3a-Lrp5 mediated Bicuspid Aortic Valve Disease

  11. No Access

    Book Chapter

    Pages 67-80

    Mouse Models of Calcific Aortic Valve Disease

  12. No Access

    Book Chapter

    Pages 81-94

    Hemodynamic Mechanisms of Bicuspid Aortic Valve Calcification and Aortopathy

  13. No Access

    Book Chapter

    Pages 95-106

    Bioreactor and Biomaterial Platforms for Investigation of Mitral Valve Biomechanics and Mechanobiology

  14. No Access

    Book Chapter

    Pages 107-116

    Identification of Early Pathological Events in Calcific Aortic Valve Disease by Molecular Imaging

  15. No Access

    Book Chapter

    Pages 117-126

    Role of Ectonucleotidases and Purinergic Receptors in Calcific Aortic Valve Disease

  16. No Access

    Book Chapter

    Pages 127-130

    In Vitro Model of Drug Testing

  17. No Access

    Book Chapter

    Pages 131-138

    Application of the LDL-Density-Pressure Theory: The Mitral Valve

  18. No Access

    Book Chapter

    Pages 139-146

    Application of the LDL-Density-Radius Theory: The Aortic Valve

  19. Back Matter

    Pages 147-150